1NEK
Complex II (Succinate Dehydrogenase) From E. Coli with ubiquinone bound
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0000104 | molecular_function | succinate dehydrogenase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0008177 | molecular_function | succinate dehydrogenase (quinone) activity |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0009060 | biological_process | aerobic respiration |
| A | 0009061 | biological_process | anaerobic respiration |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| A | 0019646 | biological_process | aerobic electron transport chain |
| A | 0022900 | biological_process | electron transport chain |
| A | 0045281 | cellular_component | succinate dehydrogenase complex |
| A | 0045282 | cellular_component | plasma membrane succinate dehydrogenase complex |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006099 | biological_process | tricarboxylic acid cycle |
| B | 0008177 | molecular_function | succinate dehydrogenase (quinone) activity |
| B | 0009055 | molecular_function | electron transfer activity |
| B | 0009060 | biological_process | aerobic respiration |
| B | 0016020 | cellular_component | membrane |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019646 | biological_process | aerobic electron transport chain |
| B | 0022904 | biological_process | respiratory electron transport chain |
| B | 0045281 | cellular_component | succinate dehydrogenase complex |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051536 | molecular_function | iron-sulfur cluster binding |
| B | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| B | 0051538 | molecular_function | 3 iron, 4 sulfur cluster binding |
| B | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006099 | biological_process | tricarboxylic acid cycle |
| C | 0008177 | molecular_function | succinate dehydrogenase (quinone) activity |
| C | 0009055 | molecular_function | electron transfer activity |
| C | 0009060 | biological_process | aerobic respiration |
| C | 0016020 | cellular_component | membrane |
| C | 0017004 | biological_process | cytochrome complex assembly |
| C | 0019646 | biological_process | aerobic electron transport chain |
| C | 0020037 | molecular_function | heme binding |
| C | 0045281 | cellular_component | succinate dehydrogenase complex |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0048039 | molecular_function | ubiquinone binding |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0006099 | biological_process | tricarboxylic acid cycle |
| D | 0009055 | molecular_function | electron transfer activity |
| D | 0009060 | biological_process | aerobic respiration |
| D | 0016020 | cellular_component | membrane |
| D | 0017004 | biological_process | cytochrome complex assembly |
| D | 0019646 | biological_process | aerobic electron transport chain |
| D | 0020037 | molecular_function | heme binding |
| D | 0045281 | cellular_component | succinate dehydrogenase complex |
| D | 0046872 | molecular_function | metal ion binding |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 12 |
| 詳細 | BINDING SITE FOR RESIDUE OAA A 589 |
| 鎖名 | 残基 |
| A | GLY51 |
| A | GLY402 |
| A | FAD601 |
| A | HOH614 |
| A | PHE126 |
| A | HIS242 |
| A | THR254 |
| A | GLU255 |
| A | ARG286 |
| A | HIS354 |
| A | ARG399 |
| A | GLY401 |
| site_id | AC2 |
| 残基数 | 6 |
| 詳細 | BINDING SITE FOR RESIDUE CA A 590 |
| 鎖名 | 残基 |
| A | TYR355 |
| A | MET356 |
| A | MET357 |
| A | GLY358 |
| A | GLU388 |
| A | ALA390 |
| site_id | AC3 |
| 残基数 | 2 |
| 詳細 | BINDING SITE FOR RESIDUE CA B 311 |
| 鎖名 | 残基 |
| B | ASP187 |
| B | THR190 |
| site_id | AC4 |
| 残基数 | 36 |
| 詳細 | BINDING SITE FOR RESIDUE FAD A 601 |
| 鎖名 | 残基 |
| A | GLY14 |
| A | ALA15 |
| A | GLY16 |
| A | GLY17 |
| A | ALA18 |
| A | SER37 |
| A | LYS38 |
| A | SER44 |
| A | HIS45 |
| A | THR46 |
| A | SER48 |
| A | ALA49 |
| A | GLN50 |
| A | GLY51 |
| A | GLY52 |
| A | TRP164 |
| A | TYR165 |
| A | ALA166 |
| A | ALA201 |
| A | THR202 |
| A | GLY203 |
| A | THR213 |
| A | ASN214 |
| A | ASP221 |
| A | LEU252 |
| A | TYR355 |
| A | GLY387 |
| A | GLU388 |
| A | ARG399 |
| A | GLY402 |
| A | ASN403 |
| A | SER404 |
| A | LEU405 |
| A | LEU408 |
| A | OAA589 |
| A | HOH617 |
| site_id | AC5 |
| 残基数 | 9 |
| 詳細 | BINDING SITE FOR RESIDUE FES B 302 |
| 鎖名 | 残基 |
| B | SER54 |
| B | CYS55 |
| B | ARG56 |
| B | GLY58 |
| B | VAL59 |
| B | CYS60 |
| B | GLY61 |
| B | ASP63 |
| B | CYS75 |
| site_id | AC6 |
| 残基数 | 8 |
| 詳細 | BINDING SITE FOR RESIDUE SF4 B 303 |
| 鎖名 | 残基 |
| B | CYS149 |
| B | ILE150 |
| B | CYS152 |
| B | ALA153 |
| B | CYS155 |
| B | ALA173 |
| B | CYS216 |
| B | LEU220 |
| site_id | AC7 |
| 残基数 | 10 |
| 詳細 | BINDING SITE FOR RESIDUE F3S B 304 |
| 鎖名 | 残基 |
| B | CYS159 |
| B | PRO172 |
| B | CYS206 |
| B | HIS207 |
| B | SER208 |
| B | ILE209 |
| B | MET210 |
| B | ASN211 |
| B | CYS212 |
| B | THR223 |
| site_id | AC8 |
| 残基数 | 19 |
| 詳細 | BINDING SITE FOR RESIDUE HEM C 305 |
| 鎖名 | 残基 |
| D | GLY75 |
| D | MET76 |
| D | GLN78 |
| B | HIS207 |
| C | HIS30 |
| C | ARG31 |
| C | GLY34 |
| C | THR37 |
| C | PHE38 |
| C | HIS84 |
| C | VAL85 |
| C | GLY88 |
| C | ILE89 |
| C | CDN308 |
| C | HOH311 |
| D | ALA23 |
| D | THR27 |
| D | ILE68 |
| D | HIS71 |
| site_id | AC9 |
| 残基数 | 7 |
| 詳細 | BINDING SITE FOR RESIDUE UQ2 D 306 |
| 鎖名 | 残基 |
| B | TRP164 |
| B | ILE209 |
| C | LEU15 |
| C | PHE20 |
| C | SER27 |
| C | ILE28 |
| D | TYR83 |
| site_id | BC1 |
| 残基数 | 20 |
| 詳細 | BINDING SITE FOR RESIDUE CDN C 308 |
| 鎖名 | 残基 |
| C | VAL41 |
| C | LEU44 |
| C | SER51 |
| C | ALA61 |
| C | SER62 |
| C | LEU78 |
| C | VAL115 |
| C | LEU123 |
| C | VAL126 |
| C | LEU127 |
| C | TRP129 |
| C | HEM305 |
| C | EPH309 |
| D | ILE30 |
| D | PHE37 |
| D | GLY41 |
| D | LEU43 |
| D | TRP48 |
| D | ILE68 |
| D | HOH315 |
| site_id | BC2 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE EPH C 309 |
| 鎖名 | 残基 |
| C | LYS107 |
| C | LYS111 |
| C | TRP129 |
| C | CDN308 |
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
| site_id | PS01000 |
| 残基数 | 25 |
| 詳細 | SDH_CYT_1 Succinate dehydrogenase cytochrome b subunit signature 1. RPVnldLqtirfpItaiaSilHRvS |
| 鎖名 | 残基 | 詳細 |
| C | ARG9-SER33 |
| site_id | PS01001 |
| 残基数 | 14 |
| 詳細 | SDH_CYT_2 Succinate dehydrogenase cytochrome b subunit signature 2. HvvvGIRHMmMDfG |
| 鎖名 | 残基 | 詳細 |
| C | HIS84-GLY97 |
| site_id | PS00504 |
| 残基数 | 10 |
| 詳細 | FRD_SDH_FAD_BINDING Fumarate reductase / succinate dehydrogenase FAD-binding site. RSHTvsAqGG |
| 鎖名 | 残基 | 詳細 |
| A | ARG43-GLY52 |
| site_id | PS00198 |
| 残基数 | 12 |
| 詳細 | 4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiLCAcCStSCP |
| 鎖名 | 残基 | 詳細 |
| B | CYS149-PRO160 |
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 23 |
| 詳細 | TOPO_DOM: Cytoplasmic => ECO:0000305 |
| 鎖名 | 残基 | 詳細 |
| D | MET1-ASP15 | |
| B | CYS216 | |
| D | THR81-ARG90 | |
| B | CYS75 | |
| B | CYS149 | |
| B | CYS152 | |
| B | CYS155 | |
| B | CYS159 | |
| B | CYS206 | |
| B | CYS212 |
| site_id | SWS_FT_FI2 |
| 残基数 | 65 |
| 詳細 | TRANSMEM: Helical |
| 鎖名 | 残基 | 詳細 |
| D | PHE16-PHE36 | |
| D | VAL59-LEU80 | |
| D | LEU91-VAL115 | |
| A | GLU388 | |
| A | SER404 |
| site_id | SWS_FT_FI3 |
| 残基数 | 21 |
| 詳細 | TOPO_DOM: Periplasmic => ECO:0000305 |
| 鎖名 | 残基 | 詳細 |
| D | PHE37-LYS58 | |
| A | THR254 | |
| A | HIS354 | |
| A | ARG399 |
| site_id | SWS_FT_FI4 |
| 残基数 | 1 |
| 詳細 | BINDING: axial binding residue |
| 鎖名 | 残基 | 詳細 |
| D | HIS71 |
| site_id | SWS_FT_FI5 |
| 残基数 | 1 |
| 詳細 | BINDING: BINDING => ECO:0000269|PubMed:12560550 |
| 鎖名 | 残基 | 詳細 |
| D | TYR83 |
