Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR CHAIN C OF INHIBITOR OM00-3 |
| Chain | Residue |
| A | GLY11 |
| A | ILE110 |
| A | GLU125 |
| A | ARG128 |
| A | TRP197 |
| A | TYR198 |
| A | ASP228 |
| A | GLY230 |
| A | THR231 |
| A | THR232 |
| A | ARG235 |
| A | GLN12 |
| A | ARG307 |
| A | HOH398 |
| A | HOH419 |
| C | HOH15 |
| C | HOH52 |
| C | HOH85 |
| C | HOH225 |
| A | LEU30 |
| A | ASP32 |
| A | GLY34 |
| A | PRO70 |
| A | TYR71 |
| A | THR72 |
| A | GLN73 |
| site_id | AC2 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR CHAIN D OF INHIBITOR OM00-3 |
| Chain | Residue |
| B | GLY11 |
| B | LEU30 |
| B | ASP32 |
| B | GLY34 |
| B | PRO70 |
| B | TYR71 |
| B | THR72 |
| B | GLN73 |
| B | ILE110 |
| B | GLU125 |
| B | ARG128 |
| B | TYR198 |
| B | ASP228 |
| B | GLY230 |
| B | THR231 |
| B | THR232 |
| B | ARG235 |
| B | ARG307 |
| B | HOH398 |
| B | HOH433 |
| B | HOH519 |
| D | HOH313 |
| D | HOH393 |
| D | HOH433 |
| D | HOH449 |
| D | HOH450 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE29-VAL40 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP32 | |
| A | ASP228 | |
| B | LEU80 | |
| B | PRO276 | |
| Chain | Residue | Details |
| A | LYS65 | |
| B | GLN266 | |
| B | ALA272 | |
| B | TYR286 | |
| B | LEU287 | |
| B | GLN294 | |
| A | LYS214 | |
| A | LYS218 | |
| A | LYS224 | |
| A | LYS238 | |
| A | LYS239 | |
| A | LYS246 | |
| B | SER113 | |
| B | TRP262 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN92 | |
| A | ASN111 | |
| A | ASN162 | |
| A | ASN293 | |
| B | LEU140 | |
| B | PHE159 | |
| B | GLY210 | |
| B | PHE341 | |
