1K6T
LACK OF SYNERGY FOR INHIBITORS TARGETING A MULTI-DRUG RESISTANT HIV-1 PROTEASE
GO（遺伝子オントロジー）由来の情報
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 3 |
| 詳細 | BINDING SITE FOR RESIDUE ACT A 502 |
| 鎖名 | 残基 |
| A | PRO1 |
| B | HIS69 |
| B | LYS70 |
| site_id | AC2 |
| 残基数 | 5 |
| 詳細 | BINDING SITE FOR RESIDUE ACT A 503 |
| 鎖名 | 残基 |
| A | LYS7 |
| A | ARG8 |
| A | HOH537 |
| A | HOH538 |
| B | ARG87 |
| site_id | AC3 |
| 残基数 | 6 |
| 詳細 | BINDING SITE FOR RESIDUE ACT A 506 |
| 鎖名 | 残基 |
| A | GLY17 |
| B | ARG14 |
| B | GLY17 |
| B | HOH542 |
| B | HOH568 |
| A | GLY16 |
| site_id | AC4 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ACT B 508 |
| 鎖名 | 残基 |
| B | PRO1 |
| B | ARG57 |
| B | HIS69 |
| B | HOH559 |
| site_id | AC5 |
| 残基数 | 19 |
| 詳細 | BINDING SITE FOR RESIDUE XN1 B 509 |
| 鎖名 | 残基 |
| A | TRP6 |
| A | ARG8 |
| A | ASP25 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| A | VAL84 |
| A | HOH508 |
| B | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP29 |
| B | ASP30 |
| B | VAL32 |
| B | GLY48 |
| B | ILE50 |
| B | PRO81 |
| B | HOH522 |
| B | HOH558 |
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
| site_id | PS00141 |
| 残基数 | 12 |
| 詳細 | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL |
| 鎖名 | 残基 | 詳細 |
| A | ALA22-LEU33 |
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 2 |
| 詳細 | SITE: Cleavage; by viral protease => ECO:0000250 |
| 鎖名 | 残基 | 詳細 |
| A | LEU76 | |
| B | LEU76 |
| site_id | SWS_FT_FI2 |
| 残基数 | 2 |
| 詳細 | MOD_RES: Phosphotyrosine; by host => ECO:0000250 |
| 鎖名 | 残基 | 詳細 |
| A | LEU76 | |
| B | LEU76 |
