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1JUO

Crystal Structure of Calcium-free Human Sorcin: A Member of the Penta-EF-Hand Protein Family

GO(遺伝子オントロジー)由来の情報
鎖名GO(遺伝子オントロジー)id名前空間内容
A0001508biological_processaction potential
A0002020molecular_functionprotease binding
A0005102molecular_functionsignaling receptor binding
A0005246molecular_functioncalcium channel regulator activity
A0005509molecular_functioncalcium ion binding
A0005515molecular_functionprotein binding
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005789cellular_componentendoplasmic reticulum membrane
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006816biological_processcalcium ion transport
A0006880biological_processintracellular sequestering of iron ion
A0006942biological_processregulation of striated muscle contraction
A0007165biological_processsignal transduction
A0007507biological_processheart development
A0007517biological_processmuscle organ development
A0008016biological_processregulation of heart contraction
A0010459biological_processnegative regulation of heart rate
A0010649biological_processregulation of cell communication by electrical coupling
A0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
A0016020cellular_componentmembrane
A0016529cellular_componentsarcoplasmic reticulum
A0030018cellular_componentZ disc
A0030315cellular_componentT-tubule
A0031982cellular_componentvesicle
A0033017cellular_componentsarcoplasmic reticulum membrane
A0035774biological_processpositive regulation of insulin secretion involved in cellular response to glucose stimulus
A0042584cellular_componentchromaffin granule membrane
A0044325molecular_functiontransmembrane transporter binding
A0046872molecular_functionmetal ion binding
A0046982molecular_functionprotein heterodimerization activity
A0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
A0051924biological_processregulation of calcium ion transport
A0055118biological_processnegative regulation of cardiac muscle contraction
A0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
A0070062cellular_componentextracellular exosome
A0086004biological_processregulation of cardiac muscle cell contraction
A0140297molecular_functionDNA-binding transcription factor binding
A1901077biological_processregulation of relaxation of muscle
A1901841biological_processregulation of high voltage-gated calcium channel activity
A1901844biological_processregulation of cell communication by electrical coupling involved in cardiac conduction
B0001508biological_processaction potential
B0002020molecular_functionprotease binding
B0005102molecular_functionsignaling receptor binding
B0005246molecular_functioncalcium channel regulator activity
B0005509molecular_functioncalcium ion binding
B0005515molecular_functionprotein binding
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005789cellular_componentendoplasmic reticulum membrane
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006816biological_processcalcium ion transport
B0006880biological_processintracellular sequestering of iron ion
B0006942biological_processregulation of striated muscle contraction
B0007165biological_processsignal transduction
B0007507biological_processheart development
B0007517biological_processmuscle organ development
B0008016biological_processregulation of heart contraction
B0010459biological_processnegative regulation of heart rate
B0010649biological_processregulation of cell communication by electrical coupling
B0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
B0016020cellular_componentmembrane
B0016529cellular_componentsarcoplasmic reticulum
B0030018cellular_componentZ disc
B0030315cellular_componentT-tubule
B0031982cellular_componentvesicle
B0033017cellular_componentsarcoplasmic reticulum membrane
B0035774biological_processpositive regulation of insulin secretion involved in cellular response to glucose stimulus
B0042584cellular_componentchromaffin granule membrane
B0044325molecular_functiontransmembrane transporter binding
B0046872molecular_functionmetal ion binding
B0046982molecular_functionprotein heterodimerization activity
B0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
B0051924biological_processregulation of calcium ion transport
B0055118biological_processnegative regulation of cardiac muscle contraction
B0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
B0070062cellular_componentextracellular exosome
B0086004biological_processregulation of cardiac muscle cell contraction
B0140297molecular_functionDNA-binding transcription factor binding
B1901077biological_processregulation of relaxation of muscle
B1901841biological_processregulation of high voltage-gated calcium channel activity
B1901844biological_processregulation of cell communication by electrical coupling involved in cardiac conduction
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
site_idPS00018
残基数13
詳細EF_HAND_1 EF-hand calcium-binding domain. DRDMSGTMGfnEF
鎖名残基詳細
AASP83-PHE95
AASP113-LEU125

SwissProt/UniProtに記載されている蛋白質分子機能情報
site_idSWS_FT_FI1
残基数20
詳細BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448
鎖名残基詳細
AASP83
AGLU124
BASP83
BASP85
BSER87
BTHR89
BGLU94
BASP113
BASP115
BSER117
BTHR119
AASP85
BGLU124
ASER87
ATHR89
AGLU94
AASP113
AASP115
ASER117
ATHR119

217705

件を2024-03-27に公開中

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