1JL2
Crystal structure of TCEO RNase H-a chimera combining the folding core from T. thermophilus RNase H and the remaining region of E. coli RNase H
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 8 |
| 詳細 | BINDING: BINDING => ECO:0000269|PubMed:1311386 |
| 鎖名 | 残基 | 詳細 |
| A | ASP10 | |
| A | ASP135 | |
| B | ASP10 | |
| B | ASP135 | |
| C | ASP10 | |
| C | ASP135 | |
| D | ASP10 | |
| D | ASP135 |
| site_id | SWS_FT_FI2 |
| 残基数 | 8 |
| 詳細 | BINDING: BINDING => ECO:0000250 |
| 鎖名 | 残基 | 詳細 |
| A | GLU48 | |
| B | GLU48 | |
| C | GLU48 | |
| D | GLU48 | |
| A | ASP70 | |
| B | ASP70 | |
| C | ASP70 | |
| D | ASP70 |
CSAにおける酵素触媒機能の情報
| site_id | MCSA1 |
| 残基数 | 5 |
| 詳細 | M-CSA 163 |
| 鎖名 | 残基 | 詳細 |
| A | ASP10 | metal ligand |
| A | GLY11 | metal ligand |
| A | GLU48 | increase acidity, increase basicity, unknown |
| A | HIS125 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, unknown |
| A | ASP135 | increase acidity, metal ligand, proton acceptor, proton donor |
| site_id | MCSA2 |
| 残基数 | 5 |
| 詳細 | M-CSA 163 |
| 鎖名 | 残基 | 詳細 |
| B | ASP10 | metal ligand |
| B | GLY11 | metal ligand |
| B | GLU48 | increase acidity, increase basicity, unknown |
| B | HIS125 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, unknown |
| B | ASP135 | increase acidity, metal ligand, proton acceptor, proton donor |
| site_id | MCSA3 |
| 残基数 | 5 |
| 詳細 | M-CSA 163 |
| 鎖名 | 残基 | 詳細 |
| C | ASP10 | metal ligand |
| C | GLY11 | metal ligand |
| C | GLU48 | increase acidity, increase basicity, unknown |
| C | HIS125 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, unknown |
| C | ASP135 | increase acidity, metal ligand, proton acceptor, proton donor |
| site_id | MCSA4 |
| 残基数 | 5 |
| 詳細 | M-CSA 163 |
| 鎖名 | 残基 | 詳細 |
| D | ASP10 | metal ligand |
| D | GLY11 | metal ligand |
| D | GLU48 | increase acidity, increase basicity, unknown |
| D | HIS125 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, unknown |
| D | ASP135 | increase acidity, metal ligand, proton acceptor, proton donor |
