1HW2

FADR-DNA COMPLEX: TRANSCRIPTIONAL CONTROL OF FATTY ACID METABOLISM IN ECHERICHIA COLI

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000062	molecular_function	fatty-acyl-CoA binding
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006629	biological_process	lipid metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0019217	biological_process	regulation of fatty acid metabolic process
A	0042803	molecular_function	protein homodimerization activity
A	0045723	biological_process	positive regulation of fatty acid biosynthetic process
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0045893	biological_process	positive regulation of DNA-templated transcription
B	0000062	molecular_function	fatty-acyl-CoA binding
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006355	biological_process	regulation of DNA-templated transcription
B	0006629	biological_process	lipid metabolic process
B	0006631	biological_process	fatty acid metabolic process
B	0019217	biological_process	regulation of fatty acid metabolic process
B	0042803	molecular_function	protein homodimerization activity
B	0045723	biological_process	positive regulation of fatty acid biosynthetic process
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0045893	biological_process	positive regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG E 23

Chain	Residue
A	GLU36
B	GLU221

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	70
Details	DNA_BIND: H-T-H motif => ECO:0000269|PubMed:11279025, ECO:0000269|PubMed:11296236

Chain	Residue	Details
A	GLU34-THR69
B	GLU34-THR69

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:11296236

Chain	Residue	Details
A	ASP99
A	SER103
A	ARG213
A	SER219
B	ASP99
B	SER103
B	ARG213
B	SER219

---