1H6F
Human TBX3, a transcription factor responsible for ulnar-mammary syndrome, bound to a palindromic DNA site
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000978 | molecular_function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0045893 | biological_process | positive regulation of DNA-templated transcription |
| B | 0000978 | molecular_function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0045893 | biological_process | positive regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A1286 |
| Chain | Residue |
| A | HOH2015 |
| A | HOH2016 |
| A | HOH2049 |
| A | HOH2107 |
| A | HOH2108 |
| A | HOH2109 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 226 |
| Details | DNA_BIND: T-box; first part => ECO:0000255|PROSITE-ProRule:PRU00201 |
| Chain | Residue | Details |
| A | LEU107-THR220 | |
| B | LEU107-THR220 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 128 |
| Details | DNA_BIND: T-box; second part => ECO:0000255|PROSITE-ProRule:PRU00201 |
| Chain | Residue | Details |
