1C8J
CRYSTAL STRUCTURE OF CYTOCHROME P450CAM MUTANT (F87W/Y96F)
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006707 | biological_process | cholesterol catabolic process |
| A | 0008395 | molecular_function | steroid hydroxylase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0018683 | molecular_function | camphor 5-monooxygenase activity |
| A | 0019383 | biological_process | (+)-camphor catabolic process |
| A | 0020037 | molecular_function | heme binding |
| A | 0036199 | molecular_function | cholest-4-en-3-one 26-monooxygenase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006707 | biological_process | cholesterol catabolic process |
| B | 0008395 | molecular_function | steroid hydroxylase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| B | 0018683 | molecular_function | camphor 5-monooxygenase activity |
| B | 0019383 | biological_process | (+)-camphor catabolic process |
| B | 0020037 | molecular_function | heme binding |
| B | 0036199 | molecular_function | cholest-4-en-3-one 26-monooxygenase activity |
| B | 0046872 | molecular_function | metal ion binding |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 20 |
| 詳細 | BINDING SITE FOR RESIDUE HEM A 417 |
| 鎖名 | 残基 |
| A | PRO100 |
| A | ASP297 |
| A | ARG299 |
| A | GLN322 |
| A | THR349 |
| A | PHE350 |
| A | GLY351 |
| A | HIS355 |
| A | CYS357 |
| A | GLY359 |
| A | HOH486 |
| A | THR101 |
| A | HOH490 |
| A | GLN108 |
| A | ARG112 |
| A | LEU244 |
| A | LEU245 |
| A | GLY248 |
| A | GLY249 |
| A | THR252 |
| site_id | AC2 |
| 残基数 | 21 |
| 詳細 | BINDING SITE FOR RESIDUE HEM B 417 |
| 鎖名 | 残基 |
| B | PRO100 |
| B | THR101 |
| B | GLN108 |
| B | ARG112 |
| B | PHE163 |
| B | LEU244 |
| B | LEU245 |
| B | GLY248 |
| B | GLY249 |
| B | THR252 |
| B | VAL295 |
| B | ASP297 |
| B | ARG299 |
| B | GLN322 |
| B | THR349 |
| B | PHE350 |
| B | GLY351 |
| B | HIS355 |
| B | CYS357 |
| B | GLY359 |
| B | HOH435 |
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
| site_id | PS00086 |
| 残基数 | 10 |
| 詳細 | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGhGSHLCLG |
| 鎖名 | 残基 | 詳細 |
| A | PHE350-GLY359 |
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 2 |
| 詳細 | BINDING: axial binding residue |
| 鎖名 | 残基 | 詳細 |
| A | LEU358 | |
| B | LEU358 |
CSAにおける酵素触媒機能の情報
| site_id | MCSA1 |
| 残基数 | 6 |
| 詳細 | M-CSA 133 |
| 鎖名 | 残基 | 詳細 |
| A | PRO187 | hydrogen bond donor, proton acceptor, proton donor, proton relay |
| A | THR252 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay |
| A | VAL253 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay |
| A | LEU358 | electrostatic stabiliser, hydrogen bond acceptor, metal ligand |
| A | GLY359 | electrostatic stabiliser, hydrogen bond donor |
| A | GLN360 | electrostatic stabiliser, hydrogen bond donor |
| site_id | MCSA2 |
| 残基数 | 6 |
| 詳細 | M-CSA 133 |
| 鎖名 | 残基 | 詳細 |
| B | PRO187 | hydrogen bond donor, proton acceptor, proton donor, proton relay |
| B | THR252 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay |
| B | VAL253 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay |
| B | LEU358 | electrostatic stabiliser, hydrogen bond acceptor, metal ligand |
| B | GLY359 | electrostatic stabiliser, hydrogen bond donor |
| B | GLN360 | electrostatic stabiliser, hydrogen bond donor |
