Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1AJE

CDC42 FROM HUMAN, NMR, 20 STRUCTURES

Functional Information from GO Data
ChainGOidnamespacecontents
A0000139cellular_componentGolgi membrane
A0000166molecular_functionnucleotide binding
A0000322cellular_componentstorage vacuole
A0002040biological_processsprouting angiogenesis
A0003015biological_processheart process
A0003161biological_processcardiac conduction system development
A0003253biological_processcardiac neural crest cell migration involved in outflow tract morphogenesis
A0003924molecular_functionGTPase activity
A0003925molecular_functionG protein activity
A0005515molecular_functionprotein binding
A0005525molecular_functionGTP binding
A0005737cellular_componentcytoplasm
A0005789cellular_componentendoplasmic reticulum membrane
A0005813cellular_componentcentrosome
A0005819cellular_componentspindle
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005886cellular_componentplasma membrane
A0005911cellular_componentcell-cell junction
A0005925cellular_componentfocal adhesion
A0006897biological_processendocytosis
A0006911biological_processphagocytosis, engulfment
A0007015biological_processactin filament organization
A0007030biological_processGolgi organization
A0007088biological_processregulation of mitotic nuclear division
A0007097biological_processnuclear migration
A0007163biological_processestablishment or maintenance of cell polarity
A0007229biological_processintegrin-mediated signaling pathway
A0007264biological_processsmall GTPase-mediated signal transduction
A0007399biological_processnervous system development
A0008104biological_processprotein localization
A0009653biological_processanatomical structure morphogenesis
A0010591biological_processregulation of lamellipodium assembly
A0010592biological_processpositive regulation of lamellipodium assembly
A0016020cellular_componentmembrane
A0016787molecular_functionhydrolase activity
A0017119cellular_componentGolgi transport complex
A0019901molecular_functionprotein kinase binding
A0021762biological_processsubstantia nigra development
A0030036biological_processactin cytoskeleton organization
A0030141cellular_componentsecretory granule
A0030154biological_processcell differentiation
A0030175cellular_componentfilopodium
A0030225biological_processmacrophage differentiation
A0030307biological_processpositive regulation of cell growth
A0030335biological_processpositive regulation of cell migration
A0030425cellular_componentdendrite
A0030496cellular_componentmidbody
A0030742molecular_functionGTP-dependent protein binding
A0031252cellular_componentcell leading edge
A0031256cellular_componentleading edge membrane
A0031274biological_processpositive regulation of pseudopodium assembly
A0031333biological_processnegative regulation of protein-containing complex assembly
A0031435molecular_functionmitogen-activated protein kinase kinase kinase binding
A0031996molecular_functionthioesterase binding
A0032427molecular_functionGBD domain binding
A0032467biological_processpositive regulation of cytokinesis
A0032488biological_processCdc42 protein signal transduction
A0032956biological_processregulation of actin cytoskeleton organization
A0032991cellular_componentprotein-containing complex
A0034191molecular_functionapolipoprotein A-I receptor binding
A0034329biological_processcell junction assembly
A0034332biological_processadherens junction organization
A0035050biological_processembryonic heart tube development
A0035088biological_processestablishment or maintenance of apical/basal cell polarity
A0036336biological_processdendritic cell migration
A0036464cellular_componentcytoplasmic ribonucleoprotein granule
A0038189biological_processneuropilin signaling pathway
A0042802molecular_functionidentical protein binding
A0042995cellular_componentcell projection
A0043005cellular_componentneuron projection
A0043025cellular_componentneuronal cell body
A0043197cellular_componentdendritic spine
A0043227cellular_componentmembrane-bounded organelle
A0043410biological_processpositive regulation of MAPK cascade
A0043525biological_processpositive regulation of neuron apoptotic process
A0044788biological_processmodulation by host of viral process
A0045177cellular_componentapical part of cell
A0045198biological_processestablishment of epithelial cell apical/basal polarity
A0045335cellular_componentphagocytic vesicle
A0045740biological_processpositive regulation of DNA replication
A0046330biological_processpositive regulation of JNK cascade
A0046847biological_processfilopodium assembly
A0048549biological_processpositive regulation of pinocytosis
A0048664biological_processneuron fate determination
A0051130biological_processpositive regulation of cellular component organization
A0051233cellular_componentspindle midzone
A0051489biological_processregulation of filopodium assembly
A0051491biological_processpositive regulation of filopodium assembly
A0051492biological_processregulation of stress fiber assembly
A0051496biological_processpositive regulation of stress fiber assembly
A0051647biological_processnucleus localization
A0051649biological_processestablishment of localization in cell
A0051683biological_processestablishment of Golgi localization
A0051835biological_processpositive regulation of synapse structural plasticity
A0051897biological_processpositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
A0051988biological_processregulation of attachment of spindle microtubules to kinetochore
A0060047biological_processheart contraction
A0060071biological_processWnt signaling pathway, planar cell polarity pathway
A0060501biological_processpositive regulation of epithelial cell proliferation involved in lung morphogenesis
A0060661biological_processsubmandibular salivary gland formation
A0060997biological_processdendritic spine morphogenesis
A0061630molecular_functionubiquitin protein ligase activity
A0070062cellular_componentextracellular exosome
A0071346biological_processcellular response to type II interferon
A0071944cellular_componentcell periphery
A0072384biological_processorganelle transport along microtubule
A0072686cellular_componentmitotic spindle
A0086101biological_processendothelin receptor signaling pathway involved in heart process
A0090135biological_processactin filament branching
A0090316biological_processpositive regulation of intracellular protein transport
A0098685cellular_componentSchaffer collateral - CA1 synapse
A0098978cellular_componentglutamatergic synapse
A0099159biological_processregulation of modification of postsynaptic structure
A0099175biological_processregulation of postsynapse organization
A0099563biological_processmodification of synaptic structure
A1900026biological_processpositive regulation of substrate adhesion-dependent cell spreading
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING:
ChainResidueDetails
AGLY10
ATHR115

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AASP57

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: (Microbial infection) O-AMP-tyrosine; by Haemophilus IbpA; alternate => ECO:0000269|PubMed:19362538, ECO:0000269|PubMed:20622875
ChainResidueDetails
ATYR32

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: (Microbial infection) O-AMP-threonine; by Vibrio VopS => ECO:0000269|PubMed:19039103
ChainResidueDetails
ATHR35

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: Phosphotyrosine; by SRC => ECO:0000269|PubMed:14506284
ChainResidueDetails
ATYR64

site_idSWS_FT_FI6
Number of Residues1
DetailsCARBOHYD: (Microbial infection) O-linked (GlcNAc) tyrosine; by Photorhabdus PAU_02230; alternate => ECO:0000269|PubMed:24141704
ChainResidueDetails
ATYR32

site_idSWS_FT_FI7
Number of Residues1
DetailsCARBOHYD: (Microbial infection) O-linked (Glc) threonine; by C.difficile toxins TcdA and TcdB; alternate => ECO:0000269|PubMed:24905543, ECO:0000269|PubMed:7775453, ECO:0000269|PubMed:7777059
ChainResidueDetails
ATHR35

217705

건을2024-03-27부터공개중

PDB statisticsPDBj update infoContact PDBjnumon