5Q0A

Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-cyanopyrazin-2-yl)-3-[3-(difluoromethoxy)phenyl]sulfonylurea

Refinement Statistics

Experimental method:X-RAY DIFFRACTION (2.3 Å)

Cell axes68.61184.335279.525
Cell angles90.0090.0090.00
SpacegroupP 21 21 21
Resolution limits29.15 - 2.30
the highest resolution shell value2.330 - 2.300
R-factor0.1884
R-work0.18590
the highest resolution shell value0.345
R-free0.23600
the highest resolution shell value0.400
RMSD bond length0.007
RMSD bond angle1.006

Data Collection Statistics

Resolution limits29.15 - 2.30
the highest resolution shell value -
Number of reflections73055
Completeness99.9

Crystallization Conditions

crystal IDmethodpHpH rangetemperatureunit
1VAPOR DIFFUSION, SITTING DROP7300

Crystallization Reagents

IDcrystal IDsolution IDreagent nameconcentrationdetails
Crystallization Reagents in Literatures*
IDcrystal IDsolutionreagent nameconcentration (unit)details
Annotated Information is extracted from Literature Info*