5Q06

Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[4-(2-methyl-1,3-thiazol-4-yl)phenyl]sulfonylurea

Refinement Statistics

Experimental method:X-RAY DIFFRACTION (2.4 Å)

Cell axes67.50683.695278.843
Cell angles90.0090.0090.00
SpacegroupP 21 21 21
Resolution limits19.99 - 2.40
the highest resolution shell value2.436 - 2.400
R-factor0.1713
R-work0.16800
the highest resolution shell value0.217
R-free0.23380
the highest resolution shell value0.310
RMSD bond length0.008
RMSD bond angle0.998

Data Collection Statistics

Resolution limits19.99 - 2.40
the highest resolution shell value -
Number of reflections62733
Completeness100.0

Crystallization Conditions

crystal IDmethodpHpH rangetemperatureunit
1VAPOR DIFFUSION, SITTING DROP7300

Crystallization Reagents

IDcrystal IDsolution IDreagent nameconcentrationdetails
Crystallization Reagents in Literatures*
IDcrystal IDsolutionreagent nameconcentration (unit)details
Annotated Information is extracted from Literature Info*