5Q01

Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[4-(4,5-dichloro-2-methylpyrazol-3-yl)oxyphenyl]sulfonylurea

Refinement Statistics

Experimental method:X-RAY DIFFRACTION (2.603 Å)

Cell axes66.435294.19283.569
Cell angles90.0097.5690.00
SpacegroupP 1 21 1
Resolution limits30.41 - 2.60
the highest resolution shell value2.636 - 2.603
R-factor0.1908
R-work0.18670
the highest resolution shell value0.222
R-free0.26690
the highest resolution shell value0.333
RMSD bond length0.008
RMSD bond angle1.085

Data Collection Statistics

Resolution limits30.41 - 2.60
the highest resolution shell value -
Number of reflections76273
Completeness78.9

Crystallization Conditions

crystal IDmethodpHpH rangetemperatureunit
1VAPOR DIFFUSION, SITTING DROP7300

Crystallization Reagents

IDcrystal IDsolution IDreagent nameconcentrationdetails
Crystallization Reagents in Literatures*
IDcrystal IDsolutionreagent nameconcentration (unit)details
Annotated Information is extracted from Literature Info*