5XF8

Cryo-EM structure of the Cdt1-MCM2-7 complex in AMPPNP state

Replaces:  5H7I

Summary for 5XF8

• Entry DOI: 10.2210/pdb5xf8/pdb
• EMDB information: 6671
• Descriptor: DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, ... (7 entities in total)
• Functional Keywords: helicase, dna replication, hydrolase
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Cellular location: Nucleus: P29469 P24279 P30665 P29496 P53091; Cytoplasm : P38132 P47112
• Total number of polymer chains: 7
• Total formula weight: 677976.49

Authors

Zhai, Y.,Cheng, E.,Wu, H.,Li, N.,Yung, P.Y.,Gao, N.,Tye, B.K. (deposition date: 2017-04-09, release date: 2017-05-03)

• Primary citation: Zhai, Y.,Cheng, E.,Wu, H.,Li, N.,Yung, P.Y.,Gao, N.,Tye, B.K.; Open-ringed structure of the Cdt1-Mcm2-7 complex as a precursor of the MCM double hexamer; Nat. Struct. Mol. Biol., 24:300-308, 2017; PubMed: 28191894; DOI: 10.1038/nsmb.3374

Experimental method

ELECTRON MICROSCOPY (7.1 Å)