4CWN

Human HSP90 alpha N-terminal domain in complex with an Aminotriazoloquinazoline inhibitor

Experimental procedure

実験手法	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Source details	RIGAKU MICROMAX-007 HF
Temperature [K]	100
Detector technology	IMAGE PLATE
Collection date	2007-10-03
Detector	MAR scanner 345 mm plate
Spacegroup name	I 2 2 2
格子定数 [Å]	67.179, 90.712, 99.232
格子定数 [度]	90.00, 90.00, 90.00

精密化法

残基	30.000 - 1.800
R因子	0.19961
Rwork	0.198
R-free	0.22832
Structure solution method	OTHER
Starting model (for MR)	NONE
結合長の平均二乗偏差(RMSD) [Å]	0.007
結合角の平均二乗偏差(RMSD) [度]	1.262
Data reduction software	DENZO
Data scaling software	SCALEPACK
Refinement software	REFMAC (5.6.0117)

Quality characteristics

	Overall	Outer shell
分解能 [Å] (低)	30.000	1.860
分解能 [Å] (高)	1.800	1.800
Rmerge_l_obs	0.070	0.320
独立反射数	28100
<I/σ(I)>	19	6.4
完全性 [%]	98.6	95.9
冗長性	6.6

結晶化条件

結晶ID	方法	pH	温度	溶液条件
1