2V7A

Crystal structure of the T315I Abl mutant in complex with the inhibitor PHA-739358

Refinement Statistics

Experimental method:X-RAY DIFFRACTION (2.5 Å)

Cell axes159.757159.75756.931
Cell angles90.0090.00120.00
SpacegroupP 62
Resolution limits30.00 - 2.50
the highest resolution shell value2.560 - 2.500
R-factor0.209
R-work0.20700
the highest resolution shell value0.280
R-free0.24600
the highest resolution shell value0.324
RMSD bond length0.013
RMSD bond angle1.580

Data Collection Statistics

Resolution limits30.00 - 2.50
the highest resolution shell value -
Number of reflections29049
Rmerge_l_obs0.080
the highest resolution shell value0.050
Completeness100.0
Redundancy5
the highest resolution shell value5
I/sigma(I)2

Crystallization Conditions

crystal IDmethodpHpH rangetemperatureunit

Crystallization Reagents

IDcrystal IDsolution IDreagent nameconcentrationdetails
Crystallization Reagents in Literatures*
IDcrystal IDsolutionreagent nameconcentration (unit)details
Annotated Information is extracted from Literature Info*