2F7Z

Protein Kinase A bound to (R)-1-(1H-Indol-3-ylmethyl)-2-(2-pyridin-4-yl-[1,7]naphtyridin-5-yloxy)-ehylamine

Experimental procedure

実験手法	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Source details	RIGAKU RU200
Temperature [K]	100
Detector technology	CCD
Collection date	2002-01-21
Detector	MARRESEARCH
Wavelength(s)	1.54
Spacegroup name	P 21 21 21
格子定数 [Å]	73.134, 75.031, 80.112
格子定数 [度]	90.00, 90.00, 90.00

精密化法

残基	19.990 - 3.000
Rwork	0.246
R-free	0.34200
Structure solution method	FOURIER SYNTHESIS
結合長の平均二乗偏差(RMSD) [Å]	0.008
結合角の平均二乗偏差(RMSD) [度]	1.400
Data reduction software	HKL-2000
Data scaling software	SCALEPACK
Phasing software	CNX
Refinement software	CNX (2000)

Quality characteristics

	Overall	Outer shell
分解能 [Å] (低)	20.000	3.190
分解能 [Å] (高)	3.000	3.000
独立反射数	8196
完全性 [%]	88.9	82.6

結晶化条件

結晶ID	方法	pH	温度	溶液条件
1	VAPOR DIFFUSION, HANGING DROP		277	VAPOR DIFFUSION, HANGING DROP, temperature 277K