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coronavirus
Coronavirus, 2020. Modified from the original illustration by David S. Goodsell@RCSB PDB

The recent outbreak of the Novel Coronavirus disease (COVID-19) is a serious threat to people all over the world. In order to understand and develop an effective drug against this virus (Severe Acute Respiratory Syndrome Coronavirus 2: SARS-CoV-2), structural work on the related proteins has already started and the resultant entries are accumulating in the PDB. PDBj provides a portal page for the COVID-19 related entries for our users. New entries will be added simultaneously with the public release from the wwPDB.

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Created: 2020-10-28 (last edited: more than 1 year ago)2022-09-02
9KUR
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BU of 9kur by Molmil
Crystal structure of mAb nCoV400Fab with SARS-CoV-2 N-CTD Complex
Descriptor: 400Fab Heavy chain, 400Fab Light chain, Nucleoprotein
Authors:Xue, S.J, Chen, S.D.
Deposit date:2024-12-04
Release date:2025-10-15
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural basis of a human antibody targeting SARS-CoV-2 nucleocapsid protein dimerization domain and interfering with RNA-binding.
Commun Biol, 8, 2025
7IBM
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BU of 7ibm by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal A05 (dataset 1) from the KIT library screening campaign, data used for ground state calculation
Descriptor: Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
9HM2
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BU of 9hm2 by Molmil
A swapped dimeric form of ZO1/TJP1 PDZ2 in complex with the C-terminal peptide from protein E of SARS-CoV-2
Descriptor: Envelope small membrane protein, IODIDE ION, Tight junction protein ZO-1
Authors:Alvarez, F, Mechaly, A, Haouz, A, Caillet-Saguy, C.
Deposit date:2024-12-06
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:HTRF-based identification of small molecules targeting SARS-CoV-2 E protein interaction with ZO-1 PDZ2
Biorxiv, 2025
9JTE
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BU of 9jte by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain complexed with fox ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ...
Authors:Jun, L, Xiaoyan, N.
Deposit date:2024-10-04
Release date:2025-10-22
Method:X-RAY DIFFRACTION (3.66 Å)
Cite:Crystal structure of SARS-CoV-2 receptor binding domain complexed with fox ACE2
To Be Published
9D8H
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BU of 9d8h by Molmil
JN.1 SARS-COV-2 Spike 3-down conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Windsor, I.W, Wu, H.
Deposit date:2024-08-19
Release date:2025-10-29
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:SARS-CoV-2 JN.1 and KP.2 spike characteristics and neutralization of JN.1-derived sublineages and T cell responses from mice immunized with monovalent JN.1- and KP.2-adapted BNT162b2 COVID-19 vaccines
To Be Published
9D8J
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BU of 9d8j by Molmil
KP.2 SARS-COV-2 Spike 3-down conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Windsor, I.W, Wu, H.
Deposit date:2024-08-19
Release date:2025-10-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:SARS-CoV-2 JN.1 and KP.2 spike characteristics and neutralization of JN.1-derived sublineages and T cell responses from mice immunized with monovalent JN.1- and KP.2-adapted BNT162b2 COVID-19 vaccines
To Be Published
9H01
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BU of 9h01 by Molmil
nsp14 of SARS-CoV-2 in complex with a camelid nanobody
Descriptor: Guanine-N7 methyltransferase nsp14, ZINC ION, vhh anti-nsp14 of SARS-CoV-2
Authors:Gauffre, P, Ferron, F, Canard, B.
Deposit date:2024-10-07
Release date:2025-10-29
Method:X-RAY DIFFRACTION (2.533 Å)
Cite:Crystallographic structure of nsp14 full length from SARS-CoV-2, stabilised by a nanobody
To Be Published
9K6Y
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BU of 9k6y by Molmil
Cryo-EM structure of SARS-CoV-2 prototype spike protein in complex with H4 Fab (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of H4, Light chain of H4, ...
Authors:Zhang, G, Li, L.J, Wu, Y, Gao, G.F.
Deposit date:2024-10-22
Release date:2025-10-29
Method:ELECTRON MICROSCOPY (2.67 Å)
Cite:Structural basis of SARS-CoV-2 prototype spike protein binding to H4 Fab
To Be Published

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PDB entries from 2025-10-29

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