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COVID-19特輯

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冠狀病毒
冠狀病毒,2020. 由David S. Goodsell @ RCSB PDB原圖修改

最近爆發的新型冠狀病毒傳染病(Novel Coronavirus disease 2019: COVID-19)對全世界的人們都構成了嚴重威脅。 為了儘早了解新病毒(Severe Acute Respiratory Syndrome Coronavirus 2: SARS-CoV-2)以開發出有效的抗病毒藥物,已經有很多科研人員開始了相關蛋白結構的研究,並且將所獲得結構數據存儲與PDB。 PDBj為用戶提供了COVID-19相關數據一覽的門戶頁面,並將於每週三更新當日新發佈的相關數據。

有關該病毒蛋白質的解說,請參見下面的“當月的分子”頁面。

“所有結構”標籤的頁面則逐一羅列了所有的數據,包括由同一研究組提交的系列數據群。 “代表性結構”標籤的頁面精選具有相同胺基酸序列的結構數據中的高分辨率數據,不重複選擇具有同一胺基酸序列的數據,即使該數據可能包含不同的配體。 “最新條目”標籤內包含本週新更新數據。


Created: 2020-09-03 (last edited: more than 1 year ago)2022-09-02
9H4B
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BU of 9h4b by Molmil
Crystal structure of SARS-CoV-2 Mpro in complex with GK-730
Descriptor: 3C-like proteinase nsp5, methyl 2-[(1S,2S)-2-[[(2S)-4-methyl-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]pentanoyl]amino]-1-oxidanyl-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propyl]-1,3-thiazole-4-carboxylate
Authors:El Kilani, H, Hilgenfeld, R.
Deposit date:2024-10-18
Release date:2025-10-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of SARS-CoV-2 Mpro in complex with GK-730
To Be Published
9K6Y
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BU of 9k6y by Molmil
Cryo-EM structure of SARS-CoV-2 prototype spike protein in complex with H4 Fab (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of H4, Light chain of H4, ...
Authors:Zhang, G, Li, L.J, Wu, Y, Gao, G.F.
Deposit date:2024-10-22
Release date:2025-10-29
Method:ELECTRON MICROSCOPY (2.67 Å)
Cite:Structural basis of SARS-CoV-2 prototype spike protein binding to H4 Fab
To Be Published

243911

數據於2025-10-29公開中

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