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coronavirus
Coronavirus, 2020. Modified from the original illustration by David S. Goodsell@RCSB PDB

The recent outbreak of the Novel Coronavirus disease (COVID-19) is a serious threat to people all over the world. In order to understand and develop an effective drug against this virus (Severe Acute Respiratory Syndrome Coronavirus 2: SARS-CoV-2), structural work on the related proteins has already started and the resultant entries are accumulating in the PDB. PDBj provides a portal page for the COVID-19 related entries for our users. New entries will be added simultaneously with the public release from the wwPDB.

An explanation article covering one of the proteins of this virus is available on the "Molecules of the Month" page below:

The tab "All entries" contains all PDB IDs, in case you want to check all independent entries, including group depositions by the same authors. The "Repr. entries" tab contains only representative PDB entries with the highest resolution, excluding duplicate entries with 100% amino acid sequence identitiy, even if they contain a different ligand. Finally, the "Latest entries" tab contains the latest entries released this week.

Created: 2020-10-28 (last edited: more than 1 year ago)2022-09-02
All entries (5527)Repr. entries (2333)Latest entries (8)
9SAR
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BU of 9sar by Molmil
Cryo-EM structure of SARS CoV-2 RdRp wild-type in complex with 20-40mer RNA incorporating ATP
Descriptor: Non-structural protein 7, Non-structural protein 8, RNA primer strand (27-MER), ...
Authors:Oliva, M.F, Das, K.
Deposit date:2025-08-07
Release date:2025-10-01
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis for selective remdesivir incorporation by SARS-CoV-2 RNA polymerase, and S759A resistance.
Biorxiv, 2025
8XZ0
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BU of 8xz0 by Molmil
Crystal complex structure of SARS-CoV-2 S bound to human ezrin
Descriptor: Ezrin, Spike protein S2'
Authors:Wang, J.M, Ma, W.F.
Deposit date:2024-01-20
Release date:2025-10-08
Method:X-RAY DIFFRACTION (2.035 Å)
Cite:Crystal complex structure of SARS-CoV-2 S bound to human ezrin
To Be Published
8XZ4
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BU of 8xz4 by Molmil
SARS-CoV-2 S and radixin complex structure
Descriptor: Radixin, Spike protein S2'
Authors:Wang, J.M, Ma, W.F.
Deposit date:2024-01-20
Release date:2025-10-08
Method:X-RAY DIFFRACTION (2.129 Å)
Cite:SARS-CoV-2 S and radixin complex structure
To Be Published
8XZ5
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BU of 8xz5 by Molmil
SARS-CoV-2 S and moesin complex structure
Descriptor: Moesin, Spike protein S2'
Authors:Wang, J.M, Ma, W.F.
Deposit date:2024-01-20
Release date:2025-10-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:SARS-CoV-2 S and moesin complex structure
To Be Published
9C7S
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BU of 9c7s by Molmil
Cryo EM structure of SARS-COV-2 (BQ 1.1) RBD in complex with Fab COV2-3891 (local refine)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab COV-3891 heavy chain, Fab COV-3891 light chain, ...
Authors:Binshtein, E, Crowe, J.E.
Deposit date:2024-06-11
Release date:2025-10-08
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo EM structure of SARS-COV-2 (BQ 1.1) RBD in complex with Fab COV2-3891 (local refine)
To Be Published
9KUR
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BU of 9kur by Molmil
Crystal structure of mAb nCoV400Fab with SARS-CoV-2 N-CTD Complex
Descriptor: 400Fab Heavy chain, 400Fab Light chain, Nucleoprotein
Authors:Xue, S.J, Chen, S.D.
Deposit date:2024-12-04
Release date:2025-10-15
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural basis of a human antibody targeting SARS-CoV-2 nucleocapsid protein dimerization domain and interfering with RNA-binding.
Commun Biol, 8, 2025
7IB8
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BU of 7ib8 by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X10590 (well A03) from the KIT library
Descriptor: 5-(4-bromophenyl)-1H-tetrazole, Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IB9
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BU of 7ib9 by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X11415 (well A09) from the KIT library
Descriptor: 3-methylnaphthalen-2-ol, Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBA
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BU of 7iba by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X13162 (well B06) from the KIT library
Descriptor: 4-(2-aminoethyl)-2-iodophenol, Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBB
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BU of 7ibb by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X13458 (well B08) from the KIT library
Descriptor: (2-bromo-1,4-phenylene)dimethanol, Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBC
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BU of 7ibc by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X15604 (well C08) from the KIT library
Descriptor: 2-[(1-methylcyclobutyl)sulfanyl]benzoic acid, Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBD
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BU of 7ibd by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X2317 (well E01) from the KIT library
Descriptor: (R)-MANDELIC ACID, Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBE
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BU of 7ibe by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X4071 (well F06) from the KIT library
Descriptor: 2,2,2-trifluoro-1-(1-methyl-1H-imidazol-2-yl)ethan-1-one, Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBF
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BU of 7ibf by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X4161 (well F07) from the KIT library
Descriptor: (3S)-3-(4-hydroxyphenyl)piperazin-2-one, Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBG
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BU of 7ibg by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X5449 (well G01) from the KIT library
Descriptor: Host translation inhibitor nsp1, methyl (1S)-2-oxocyclopentane-1-carboxylate
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBH
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BU of 7ibh by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X6553 (well G10) from the KIT library
Descriptor: (4-bromanyl-5-methyl-thiophen-2-yl)-oxidanyl-oxidanylidene-boron, Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBI
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BU of 7ibi by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 in complex with fragment X7214 (well H02) from the KIT library
Descriptor: Host translation inhibitor nsp1, N,N'-(pyridine-2,6-diyl)diacetamide
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBJ
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BU of 7ibj by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal A01 (dataset 1) from the KIT library screening campaign, data used for ground state calculation
Descriptor: Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBK
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BU of 7ibk by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal A02 (dataset 1) from the KIT library screening campaign, data used for ground state calculation
Descriptor: Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBL
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BU of 7ibl by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal A04 (dataset 2) from the KIT library screening campaign, data used for ground state calculation
Descriptor: Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBM
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BU of 7ibm by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal A05 (dataset 1) from the KIT library screening campaign, data used for ground state calculation
Descriptor: Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBN
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BU of 7ibn by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal A06 (dataset 1) from the KIT library screening campaign, data used for ground state calculation
Descriptor: Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBO
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BU of 7ibo by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal A07 (dataset 1) from the KIT library screening campaign, data used for ground state calculation
Descriptor: Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBP
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BU of 7ibp by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal A08 (dataset 1) from the KIT library screening campaign, data used for ground state calculation
Descriptor: Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025
7IBQ
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BU of 7ibq by Molmil
PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal A10 (dataset 1) from the KIT library screening campaign, data used for ground state calculation
Descriptor: Host translation inhibitor nsp1
Authors:Lennartz, F, Weiss, M.S.
Deposit date:2025-05-27
Release date:2025-10-22
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystallographic fragment screening against SARS-CoV-2 nonstructural protein 1 using the F2X-Entry Screen and a newly developed fragment library.
Acta Crystallogr D Struct Biol, 2025

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