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Yorodumi- PDB-4ane: R80N MUTANT OF NUCLEOSIDE DIPHOSPHATE KINASE FROM MYCOBACTERIUM T... -
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-Basic information
Entry | Database: PDB / ID: 4ane | ||||||
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Title | R80N MUTANT OF NUCLEOSIDE DIPHOSPHATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS | ||||||
Components | NUCLEOSIDE DIPHOSPHATE KINASENucleoside-diphosphate kinase | ||||||
Keywords | TRANSFERASE | ||||||
Function / homology | Function and homology information symbiont-mediated suppression of host innate immune response / : / purine nucleotide metabolic process / pyrimidine nucleotide metabolic process / nuclease activity / nucleoside-diphosphate kinase / UTP biosynthetic process / CTP biosynthetic process / GTP biosynthetic process / nucleoside diphosphate kinase activity ...symbiont-mediated suppression of host innate immune response / : / purine nucleotide metabolic process / pyrimidine nucleotide metabolic process / nuclease activity / nucleoside-diphosphate kinase / UTP biosynthetic process / CTP biosynthetic process / GTP biosynthetic process / nucleoside diphosphate kinase activity / phosphoprotein phosphatase activity / Prevention of phagosomal-lysosomal fusion / protein autophosphorylation / extracellular region / ATP binding / metal ion binding / plasma membrane / cytosol / cytoplasm Similarity search - Function | ||||||
Biological species | MYCOBACTERIUM TUBERCULOSIS (bacteria) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 1.9 Å | ||||||
Authors | Georgescauld, F. / Moynie, L. / Habersetzer, J. / Lascu, I. / Dautant, A. | ||||||
Citation | Journal: Acta Crystallogr.,Sect.D / Year: 2014 Title: Structure of Mycobacterium Tuberculosis Nucleoside Diphosphate Kinase R80N Mutant in Complex with Citrate Authors: Georgescauld, F. / Moynie, L. / Habersetzer, J. / Dautant, A. #1: Journal: Proteins / Year: 2002 Title: X-Ray Structure of Mycobacterium Tuberculosis Nucleoside Diphosphate Kinase. Authors: Chen, Y. / Morera, S. / Mocan, J. / Lascu, I. / Janin, J. #2: Journal: Plos One / Year: 2013 Title: Intersubunit Ionic Interactions Stabilize the Nucleoside Diphosphate Kinase of Mycobacterium Tuberculosis. Authors: Georgescauld, F. / Moynie, L. / Habersetzer, J. / Cervoni, L. / Mocan, I. / Borza, T. / Harris, P. / Dautant, A. / Lascu, I. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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PDBx/mmCIF format | 4ane.cif.gz | 320.2 KB | Display | PDBx/mmCIF format |
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PDB format | pdb4ane.ent.gz | 264 KB | Display | PDB format |
PDBx/mmJSON format | 4ane.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/an/4ane ftp://data.pdbj.org/pub/pdb/validation_reports/an/4ane | HTTPS FTP |
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-Related structure data
Related structure data | 1k44S S: Starting model for refinement |
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Similar structure data |
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-Assembly
Deposited unit |
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Noncrystallographic symmetry (NCS) | NCS domain:
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