+Open data
-Basic information
Entry | Database: PDB / ID: 1qg9 | ||||||
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Title | SECOND REPEAT (IS2MIC) FROM VOLTAGE-GATED SODIUM CHANNEL | ||||||
Components | PROTEIN (SODIUM CHANNEL PROTEIN, BRAIN II ALPHA SUBUNIT) | ||||||
Keywords | TRANSMEMBRANE CHANNEL / TRANSMEMBRANE SODIUM CHANNEL | ||||||
Function / homology | Function and homology information Phase 0 - rapid depolarisation / response to pyrethroid / membrane depolarization during action potential / sodium ion binding / voltage-gated monoatomic ion channel activity / voltage-gated sodium channel complex / voltage-gated sodium channel activity / regulation of monoatomic ion transmembrane transport / cellular response to antibiotic / neuronal action potential ...Phase 0 - rapid depolarisation / response to pyrethroid / membrane depolarization during action potential / sodium ion binding / voltage-gated monoatomic ion channel activity / voltage-gated sodium channel complex / voltage-gated sodium channel activity / regulation of monoatomic ion transmembrane transport / cellular response to antibiotic / neuronal action potential / sodium ion transmembrane transport / monoatomic cation channel activity / sensory perception of pain / response to wounding / nervous system development / calmodulin binding / axon / neuronal cell body / membrane / plasma membrane / cytoplasm Similarity search - Function | ||||||
Method | SOLUTION NMR / simulated annealing | ||||||
Authors | Doak, D.J. / Mulvey, D. / Kawaguchi, K. / Villalain, J. / Campbell, I.D. | ||||||
Citation | Journal: J.Mol.Biol. / Year: 1996 Title: Structural studies of synthetic peptides dissected from the voltage-gated sodium channel. Authors: Doak, D.G. / Mulvey, D. / Kawaguchi, K. / Villalain, J. / Campbell, I.D. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1qg9.cif.gz | 185.5 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1qg9.ent.gz | 130.5 KB | Display | PDB format |
PDBx/mmJSON format | 1qg9.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/qg/1qg9 ftp://data.pdbj.org/pub/pdb/validation_reports/qg/1qg9 | HTTPS FTP |
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-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein/peptide | Mass: 2480.853 Da / Num. of mol.: 1 / Fragment: S2 OF REPEAT I / Source method: obtained synthetically Details: SEQUENCE FROM MEMBRANES OF BRAIN CELLS OF RAT (RATTUS NORVEGICUS) References: UniProt: P08104 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||
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NMR experiment |
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NMR details | Text: SEE JOURNAL REFERENCE |
-Sample preparation
Details | Contents: MICELLE MOLAR RATIO DPC/ IS2 = 68 |
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Sample conditions | pH: 3.3 / Temperature: 303 K |
Crystal grow | *PLUS Method: other / Details: NMR |
-NMR measurement
NMR spectrometer |
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-Processing
NMR software |
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Refinement | Method: simulated annealing / Software ordinal: 1 Details: STRUCTURES HAVE BEEN RECALCULATED USING PARAMETERS PARALLHDG5.1.PRO (MICHAEL NILGES) | ||||||||||||
NMR ensemble | Conformer selection criteria: ENERGY / Conformers calculated total number: 50 / Conformers submitted total number: 30 |