- PDB-1g5j: COMPLEX OF BCL-XL WITH PEPTIDE FROM BAD -
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Basic information
Entry
Database: PDB / ID: 1g5j
Title
COMPLEX OF BCL-XL WITH PEPTIDE FROM BAD
Components
APOPTOSIS REGULATOR BCL-XBcl-2-like protein 1
BAD PROTEIN
Keywords
APOPTOSIS / complex
Function / homology
Function and homology information
ADP metabolic process / positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress / positive regulation of type B pancreatic cell development / positive regulation of glucokinase activity / BAD-BCL-2 complex / glucose catabolic process / pore complex assembly / apoptotic process in bone marrow cell / The NLRP1 inflammasome / SARS-CoV-1-mediated effects on programmed cell death ...ADP metabolic process / positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress / positive regulation of type B pancreatic cell development / positive regulation of glucokinase activity / BAD-BCL-2 complex / glucose catabolic process / pore complex assembly / apoptotic process in bone marrow cell / The NLRP1 inflammasome / SARS-CoV-1-mediated effects on programmed cell death / dendritic cell apoptotic process / dendritic cell proliferation / type B pancreatic cell proliferation / positive regulation of mononuclear cell proliferation / BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members / negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage / negative regulation of dendritic cell apoptotic process / negative regulation of execution phase of apoptosis / negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway / activation of cysteine-type endopeptidase activity / fertilization / cellular response to lipid / positive regulation of mitochondrial membrane potential / negative regulation of protein localization to plasma membrane / regulation of mitochondrial membrane permeability / regulation of growth / positive regulation of T cell differentiation / AKT phosphorylates targets in the cytosol / Bcl-2 family protein complex / positive regulation of B cell differentiation / NFE2L2 regulating tumorigenic genes / response to cycloheximide / cellular response to alkaloid / NRAGE signals death through JNK / STAT5 activation downstream of FLT3 ITD mutants / hepatocyte apoptotic process / negative regulation of reproductive process / negative regulation of developmental process / negative regulation of release of cytochrome c from mitochondria / BH3 domain binding / apoptotic mitochondrial changes / germ cell development / positive regulation of insulin secretion involved in cellular response to glucose stimulus / Constitutive Signaling by AKT1 E17K in Cancer / positive regulation of proteolysis / cysteine-type endopeptidase activator activity involved in apoptotic process / positive regulation of release of cytochrome c from mitochondria / positive regulation of cysteine-type endopeptidase activity involved in apoptotic process / negative regulation of anoikis / extrinsic apoptotic signaling pathway via death domain receptors / negative regulation of extrinsic apoptotic signaling pathway in absence of ligand / Activation of BAD and translocation to mitochondria / ectopic germ cell programmed cell death / negative regulation of intrinsic apoptotic signaling pathway / positive regulation of autophagy / negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway / ATP metabolic process / extrinsic apoptotic signaling pathway / negative regulation of extrinsic apoptotic signaling pathway via death domain receptors / ovarian follicle development / extrinsic apoptotic signaling pathway in absence of ligand / negative regulation of autophagy / intrinsic apoptotic signaling pathway / release of cytochrome c from mitochondria / regulation of mitochondrial membrane potential / regulation of cytokinesis / epithelial cell proliferation / response to cytokine / positive regulation of epithelial cell proliferation / cellular response to amino acid stimulus / phospholipid binding / cellular response to gamma radiation / synaptic vesicle membrane / positive regulation of insulin secretion / endocytosis / cytokine-mediated signaling pathway / cellular response to mechanical stimulus / cellular response to nicotine / RAS processing / male gonad development / activation of cysteine-type endopeptidase activity involved in apoptotic process / intrinsic apoptotic signaling pathway in response to DNA damage / glucose homeostasis / cellular response to hypoxia / spermatogenesis / defense response to virus / protein phosphatase binding / neuron apoptotic process / nuclear membrane / Interleukin-4 and Interleukin-13 signaling / mitochondrial inner membrane / in utero embryonic development / negative regulation of neuron apoptotic process / mitochondrial outer membrane / mitochondrial matrix / positive regulation of apoptotic process / protein heterodimerization activity / centrosome / lipid binding / apoptotic process Similarity search - Function
Bcl2-associated agonist of cell death / Pro-apoptotic Bcl-2 protein, BAD / Apoptosis regulator, Bcl-X / Apoptosis regulator, Bcl-2/ BclX / Apoptosis regulator, Bcl-2, BH4 motif, conserved site / Apoptosis regulator, Bcl-2 family BH4 motif signature. / Apoptosis regulator, Bcl-2 protein, BH4 / Bcl-2 homology region 4 / Apoptosis regulator, Bcl-2 family BH4 motif profile. / BH4 Bcl-2 homology region 4 ...Bcl2-associated agonist of cell death / Pro-apoptotic Bcl-2 protein, BAD / Apoptosis regulator, Bcl-X / Apoptosis regulator, Bcl-2/ BclX / Apoptosis regulator, Bcl-2, BH4 motif, conserved site / Apoptosis regulator, Bcl-2 family BH4 motif signature. / Apoptosis regulator, Bcl-2 protein, BH4 / Bcl-2 homology region 4 / Apoptosis regulator, Bcl-2 family BH4 motif profile. / BH4 Bcl-2 homology region 4 / Blc2-like / Apoptosis Regulator Bcl-x / Apoptosis regulator, Bcl-2, BH3 motif, conserved site / Apoptosis regulator, Bcl-2 family BH3 motif signature. / Apoptosis regulator, Bcl-2, BH1 motif, conserved site / Apoptosis regulator, Bcl-2 family BH1 motif signature. / Apoptosis regulator, Bcl-2, BH2 motif, conserved site / Apoptosis regulator, Bcl-2 family BH2 motif signature. / BCL (B-Cell lymphoma); contains BH1, BH2 regions / Bcl-2 family / Bcl-2, Bcl-2 homology region 1-3 / Bcl2-like / Apoptosis regulator proteins, Bcl-2 family / BCL2-like apoptosis inhibitors family profile. / Bcl-2-like superfamily / Orthogonal Bundle / Mainly Alpha Similarity search - Domain/homology
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