- PDB-5l8a: Targeting the PEX14-PEX5 interaction by small molecules provides ... -
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基本情報
登録情報
データベース: PDB / ID: 5l8a
タイトル
Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases.
要素
Peroxin 14
キーワード
SIGNALING PROTEIN / trypanosomiasis (トリパノソーマ症) / glycosome / protein-protein interaction inhibitor / structure-based drug discovery / inhibitor (酵素阻害剤)
機能・相同性
機能・相同性情報
glycosome membrane / protein import into peroxisome matrix, docking / protein targeting to vacuole / glycosome / post-transcriptional regulation of gene expression 類似検索 - 分子機能
Component-ID: 0 / Beg auth comp-ID: SER / Beg label comp-ID: SER / End auth comp-ID: SER / End label comp-ID: SER / Refine code: 0 / Auth seq-ID: 5 - 66 / Label seq-ID: 8 - 69
解像度: 1.57→27.79 Å / Cor.coef. Fo:Fc: 0.948 / Cor.coef. Fo:Fc free: 0.916 / SU B: 5.226 / SU ML: 0.084 / 交差検証法: THROUGHOUT / ESU R: 0.147 / ESU R Free: 0.112 / 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS