- PDB-3syo: Crystal structure of the G protein-gated inward rectifier K+ chan... -
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基本情報
登録情報
データベース: PDB / ID: 3syo
タイトル
Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in complex with sodium
要素
G protein-activated inward rectifier potassium channel 2
キーワード
METAL TRANSPORT / ion channel (イオンチャネル) / potassium channel (カリウムチャネル) / inward rectification / sodium binding (ナトリウム) / PIP2 binding (ホスファチジルイノシトール4,5-ビスリン酸) / G protein binding
機能・相同性
機能・相同性情報
G-protein activated inward rectifier potassium channel activity / Activation of G protein gated Potassium channels / Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits / voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential / inward rectifier potassium channel activity / regulation of monoatomic ion transmembrane transport / parallel fiber to Purkinje cell synapse / monoatomic ion channel complex / neuronal cell body membrane / potassium ion import across plasma membrane ...G-protein activated inward rectifier potassium channel activity / Activation of G protein gated Potassium channels / Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits / voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential / inward rectifier potassium channel activity / regulation of monoatomic ion transmembrane transport / parallel fiber to Purkinje cell synapse / monoatomic ion channel complex / neuronal cell body membrane / potassium ion import across plasma membrane / potassium channel activity / G-protein alpha-subunit binding / negative regulation of insulin secretion / presynaptic membrane / 神経繊維 / 樹状突起 / 細胞膜 / 細胞膜 類似検索 - 分子機能
解像度: 3.54→41.68 Å / Cor.coef. Fo:Fc: 0.879 / Cor.coef. Fo:Fc free: 0.905 / Occupancy max: 1 / Occupancy min: 0.13 / SU B: 55.693 / SU ML: 0.404 / 交差検証法: THROUGHOUT / σ(F): 0 / ESU R Free: 0.58 / 立体化学のターゲット値: MAXIMUM LIKELIHOOD 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : WITH TLS ADDED
Rfactor
反射数
%反射
Selection details
Rfree
0.2727
566
7.1 %
RANDOM
Rwork
0.2604
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obs
0.2613
7970
92.03 %
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溶媒の処理
イオンプローブ半径: 0.8 Å / 減衰半径: 0.8 Å / VDWプローブ半径: 1.4 Å / 溶媒モデル: MASK