erythrocyte apoptotic process / maintenance of postsynaptic density structure / regulation of dendritic spine development / establishment of epithelial cell polarity / negative regulation of receptor-mediated endocytosis / protein localization to endosome / negative regulation of dendrite development / ruffle assembly / regulation of Rac protein signal transduction / negative regulation of protein localization to cell surface ...erythrocyte apoptotic process / maintenance of postsynaptic density structure / regulation of dendritic spine development / establishment of epithelial cell polarity / negative regulation of receptor-mediated endocytosis / protein localization to endosome / negative regulation of dendrite development / ruffle assembly / regulation of Rac protein signal transduction / negative regulation of protein localization to cell surface / positive regulation of keratinocyte migration / positive regulation of focal adhesion disassembly / regulation of filopodium assembly / endocytic recycling / thioesterase binding / regulation of stress fiber assembly / MET receptor recycling / filopodium membrane / protein localization to cell surface / Flemming body / TBC/RABGAPs / cortical actin cytoskeleton organization / positive regulation of actin filament polymerization / hepatocyte apoptotic process / 分裂溝 / regulation of presynapse assembly / synaptic vesicle endocytosis / endocytic vesicle / signaling adaptor activity / vesicle-mediated transport / ruffle / GTPase activator activity / cellular response to nerve growth factor stimulus / 低分子量GTPアーゼ / G protein activity / liver development / protein localization to plasma membrane / positive regulation of protein secretion / positive regulation of protein localization to plasma membrane / intracellular protein transport / positive regulation of neuron projection development / positive regulation of GTPase activity / recycling endosome membrane / GDP binding / 遊走 / presynapse / Clathrin-mediated endocytosis / nervous system development / 細胞皮質 / early endosome membrane / postsynapse / 細胞分化 / 細胞接着 / エンドソーム / 細胞周期 / 細胞分裂 / intracellular membrane-bounded organelle / focal adhesion / GTPase activity / glutamatergic synapse / GTP binding / ゴルジ体 / extracellular exosome / 核質 / 生体膜 / metal ion binding / 細胞膜 / 細胞質基質 類似検索 - 分子機能
Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat - #950 / Arf GTPase activating protein, ASAP3 / : / ASAP, PH domain / Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein / Arf GTPase activating protein / ADP-ribosylation factor 6 / BAR domain of APPL family / Arf GTPase activating protein / ArfGAP domain superfamily ...Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat - #950 / Arf GTPase activating protein, ASAP3 / : / ASAP, PH domain / Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein / Arf GTPase activating protein / ADP-ribosylation factor 6 / BAR domain of APPL family / Arf GTPase activating protein / ArfGAP domain superfamily / Putative GTPase activating protein for Arf / ARF GTPase-activating proteins domain profile. / Putative GTP-ase activating proteins for the small GTPase, ARF / BAR domain / ARFGAP/RecO-like zinc finger / Small GTPase superfamily, ARF type / small GTPase Arf family profile. / Annexin V; domain 1 / Sar1p-like members of the Ras-family of small GTPases / Small GTPase superfamily, ARF/SAR type / ADP-ribosylation factor family / ARF-like small GTPases; ARF, ADP-ribosylation factor / AH/BAR domain superfamily / Ankyrin repeat-containing domain / PH domain / PH domain profile. / Pleckstrin homology domain. / Pleckstrin homology domain / Ankyrin repeats (3 copies) / Rab subfamily of small GTPases / Ankyrin repeat profile. / Ankyrin repeat region circular profile. / ankyrin repeats / Ankyrin repeat / Ankyrin repeat-containing domain superfamily / Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat / Αソレノイド / Small GTP-binding protein domain / PH-like domain superfamily / P-loop containing nucleotide triphosphate hydrolases / P-loop containing nucleoside triphosphate hydrolase / ロスマンフォールド / Orthogonal Bundle / 3-Layer(aba) Sandwich / Mainly Alpha / Alpha Beta 類似検索 - ドメイン・相同性
フッ化アルミニウム / GUANOSINE-5'-DIPHOSPHATE / ADP-ribosylation factor 6 / Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 類似検索 - 構成要素
Arf-GAPwithSH3domain, ANKrepeatandPHdomain-containingprotein3, ADP-ribosylationfactor6 / ASAP3 / Development and differentiation-enhancing factor-like 1 / Protein up-regulated in liver ...ASAP3 / Development and differentiation-enhancing factor-like 1 / Protein up-regulated in liver cancer 1 / Arf6 / UPLC1
分子量: 54825.930 Da / 分子数: 1 断片: GAP and Ankyrin domain, residues 416-697, residues 11-175 由来タイプ: 組換発現 / 詳細: Missing the N-terminus amphipathic helix for Arf6 由来: (組換発現) Homo sapiens (ヒト), (組換発現) synthetic construct (人工物) 遺伝子: ASAP3, ARF6 / 発現宿主: Escherichia coli (大腸菌) / 参照: UniProt: Q8TDY4, PDB-3LVQ, UniProt: P62330
解像度: 3.38→29.46 Å / Cor.coef. Fo:Fc: 0.94 / Cor.coef. Fo:Fc free: 0.901 / SU B: 56.231 / SU ML: 0.451 / 交差検証法: THROUGHOUT / ESU R Free: 0.61 / 立体化学のターゲット値: MAXIMUM LIKELIHOOD / 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
Rfactor
反射数
%反射
Selection details
Rfree
0.28129
437
5 %
RANDOM
Rwork
0.20746
-
-
-
obs
0.21095
8294
100 %
-
溶媒の処理
イオンプローブ半径: 0.8 Å / 減衰半径: 0.8 Å / VDWプローブ半径: 1.2 Å / 溶媒モデル: MASK