- PDB-3fbk: Crystal structure of the C2 domain of the human regulator of G-pr... -
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基本情報
登録情報
データベース: PDB / ID: 3fbk
タイトル
Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A
要素
Regulator of G-protein signaling 3
キーワード
SIGNALING PROTEIN / all beta-sheet fold / Structural Genomics (構造ゲノミクス) / PSI-2 / Protein Structure Initiative / Northeast Structural Genomics Consortium / NESG / Alternative splicing (選択的スプライシング) / Cell membrane (細胞膜) / Cytoplasm (細胞質) / Membrane (生体膜) / Nucleus (Nucleus) / Phosphoprotein / Signal transduction inhibitor
機能・相同性
機能・相同性情報
regulation of G protein-coupled receptor signaling pathway / negative regulation of signal transduction / GTPase activator activity / G alpha (i) signalling events / G alpha (q) signalling events / G protein-coupled receptor signaling pathway / GTPase activity / 細胞核 / 細胞膜 / 細胞質基質 類似検索 - 分子機能
Regulator of G-protein signalling 3, RGS domain / RGS, subdomain 1/3 / Regulator of G protein signaling domain / RGS, subdomain 2 / RGS domain / RGS domain profile. / Regulator of G protein signalling domain / RGS domain superfamily / C2ドメイン / C2ドメイン ...Regulator of G-protein signalling 3, RGS domain / RGS, subdomain 1/3 / Regulator of G protein signaling domain / RGS, subdomain 2 / RGS domain / RGS domain profile. / Regulator of G protein signalling domain / RGS domain superfamily / C2ドメイン / C2ドメイン / Protein kinase C conserved region 2 (CalB) / C2ドメイン / C2 domain profile. / C2 domain superfamily / PDZドメイン / PDZ domain profile. / Domain present in PSD-95, Dlg, and ZO-1/2. / PDZドメイン / PDZ superfamily / PH-like domain superfamily / Immunoglobulin-like / サンドイッチ / Mainly Beta 類似検索 - ドメイン・相同性
温度: 291 K / 手法: microbatch under oil / pH: 7 詳細: Protein solution: 10 mM Tris (pH 7.5), 100 mM sodium chloride, and 5 mM DTT. Reservoir solution: 100 mM Bis-Tris Propane (pH 7), 40% PEG 1000, and 100 mM (NH4)2 SO4. , microbatch under oil, temperature 291K