登録情報 データベース : PDB / ID : 3agz 構造の表示 ダウンロードとリンクタイトル Crystal structure of human Hsp40 Hdj1 peptide-binding domain complexed with a C-terminal peptide of Hsp70 要素DnaJ homolog subfamily B member 1 peptide of Heat shock cognate 71 kDa protein 詳細キーワード CHAPERONE (シャペロン)機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
lumenal side of lysosomal membrane / regulation of protein import / negative regulation of supramolecular fiber organization / protein carrier chaperone / clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane / 先体 / Lipophagy / chaperone-mediated autophagy translocation complex disassembly / slow axonal transport / clathrin-uncoating ATPase activity ... lumenal side of lysosomal membrane / regulation of protein import / negative regulation of supramolecular fiber organization / protein carrier chaperone / clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane / 先体 / Lipophagy / chaperone-mediated autophagy translocation complex disassembly / slow axonal transport / clathrin-uncoating ATPase activity / GABA synthesis, release, reuptake and degradation / protein targeting to lysosome involved in chaperone-mediated autophagy / late endosomal microautophagy / negative regulation of inclusion body assembly / C3HC4-type RING finger domain binding / clathrin coat disassembly / negative regulation of NLRP3 inflammasome complex assembly / CHL1 interactions / ATP-dependent protein disaggregase activity / regulation of protein complex stability / membrane organization / Prp19 complex / presynaptic cytosol / positive regulation of ATP-dependent activity / protein folding chaperone complex / transcription regulator inhibitor activity / postsynaptic cytosol / Lysosome Vesicle Biogenesis / chaperone-mediated autophagy / cellular response to steroid hormone stimulus / Golgi Associated Vesicle Biogenesis / non-chaperonin molecular chaperone ATPase / ATPase activator activity / chaperone cofactor-dependent protein refolding / regulation of protein-containing complex assembly / HSF1-dependent transactivation / response to unfolded protein / オートファゴソーム / Regulation of HSF1-mediated heat shock response / Attenuation phase / Protein methylation / regulation of cellular response to heat / protein folding chaperone / ATP metabolic process / forebrain development / Hsp70 protein binding / heat shock protein binding / HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand / cellular response to starvation / mRNA Splicing - Major Pathway / lysosomal lumen / G protein-coupled receptor binding / AUF1 (hnRNP D0) binds and destabilizes mRNA / ATP-dependent protein folding chaperone / spliceosomal complex / Late endosomal microautophagy / MAPK6/MAPK4 signaling / regulation of protein stability / PKR-mediated signaling / terminal bouton / mRNA splicing, via spliceosome / Chaperone Mediated Autophagy / transcription corepressor activity / メラノソーム / unfolded protein binding / protein-macromolecule adaptor activity / フォールディング / Clathrin-mediated endocytosis / cellular response to heat / MHC class II protein complex binding / ATPase binding / protein-folding chaperone binding / protein refolding / blood microparticle / Interleukin-4 and Interleukin-13 signaling / secretory granule lumen / ficolin-1-rich granule lumen / 樹状突起スパイン / postsynaptic density / リソソーム / cadherin binding / ribonucleoprotein complex / lysosomal membrane / focal adhesion / negative regulation of DNA-templated transcription / 樹状突起 / neuronal cell body / glutamatergic synapse / ubiquitin protein ligase binding / Neutrophil degranulation / 核小体 / negative regulation of transcription by RNA polymerase II / enzyme binding / ATP hydrolysis activity / extracellular space / RNA binding / extracellular exosome / extracellular region / 核質 / ATP binding 類似検索 - 分子機能 Urease metallochaperone UreE, N-terminal domain / HSP40/DNAj peptide-binding domain / HSP40/DnaJ peptide-binding / Chaperone DnaJ, C-terminal / DnaJ C terminal domain / Nt-dnaJ domain signature. / DnaJ domain, conserved site / DnaJ domain / DnaJ molecular chaperone homology domain / dnaJ domain profile. ... Urease metallochaperone UreE, N-terminal domain / HSP40/DNAj peptide-binding domain / HSP40/DnaJ peptide-binding / Chaperone DnaJ, C-terminal / DnaJ C terminal domain / Nt-dnaJ domain signature. / DnaJ domain, conserved site / DnaJ domain / DnaJ molecular chaperone homology domain / dnaJ domain profile. / Chaperone J-domain superfamily / DnaJ domain / Heat shock hsp70 proteins family signature 2. / Heat shock hsp70 proteins family signature 1. / Heat shock hsp70 proteins family signature 3. / Heat shock protein 70, conserved site / Heat shock protein 70kD, peptide-binding domain superfamily / Heat shock protein 70 family / Hsp70 protein / Heat shock protein 70kD, C-terminal domain superfamily / ATPase, nucleotide binding domain / サンドイッチ / Mainly Beta 類似検索 - ドメイン・相同性 Heat shock cognate 71 kDa protein / DnaJ homolog subfamily B member 1 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / 分子置換 / 解像度 : 2.51 Å 詳細データ登録者 Suzuki, H. / Noguchi, S. / Satow, Y. 引用ジャーナル : Biochemistry / 年 : 2010タイトル : Peptide-binding sites as revealed by the crystal structures of the human Hsp40 Hdj1 C-terminal domain in complex with the octapeptide from human Hsp70著者 : Suzuki, H. / Noguchi, S. / Arakawa, H. / Tokida, T. / Hashimoto, M. / Satow, Y. 履歴 登録 2010年4月12日 登録サイト : PDBJ / 処理サイト : PDBJ改定 1.0 2011年2月23日 Provider : repository / タイプ : Initial release改定 1.1 2011年7月13日 Group : Version format compliance改定 1.2 2024年3月13日 Group : Data collection / Database references / カテゴリ : chem_comp_atom / chem_comp_bond / database_2Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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