登録情報 データベース : PDB / ID : 2izx 構造の表示 ダウンロードとリンクタイトル Molecular Basis of AKAP Specificity for PKA Regulatory Subunits 要素AKAP-IS CAMP-DEPENDENT PROTEIN KINASE TYPE II-ALPHA REGULATORY SUBUNIT CAMP-dependent pathway 詳細キーワード TRANSFERASE (転移酵素) / CAMP-BINDING / PHOSPHORYLATION (リン酸化) / NUCLEOTIDE-BINDING / PKA / CAMP (CAMP) / AKAP / ANCHOR (錨) / KINASE (キナーゼ) / ACETYLATION (アセチル化)機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
ROBO receptors bind AKAP5 / cAMP-dependent protein kinase regulator activity / negative regulation of cAMP-dependent protein kinase activity / nucleotide-activated protein kinase complex / cAMP-dependent protein kinase inhibitor activity / CREB1 phosphorylation through the activation of Adenylate Cyclase / PKA activation / ciliary base / cAMP-dependent protein kinase complex / protein kinase A catalytic subunit binding ... ROBO receptors bind AKAP5 / cAMP-dependent protein kinase regulator activity / negative regulation of cAMP-dependent protein kinase activity / nucleotide-activated protein kinase complex / cAMP-dependent protein kinase inhibitor activity / CREB1 phosphorylation through the activation of Adenylate Cyclase / PKA activation / ciliary base / cAMP-dependent protein kinase complex / protein kinase A catalytic subunit binding / plasma membrane raft / PKA activation in glucagon signalling / DARPP-32 events / Hedgehog 'off' state / cAMP binding / FCGR3A-mediated IL10 synthesis / Vasopressin regulates renal water homeostasis via Aquaporins / Glucagon-like Peptide-1 (GLP1) regulates insulin secretion / ADORA2B mediated anti-inflammatory cytokines production / GPER1 signaling / Factors involved in megakaryocyte development and platelet production / intracellular signal transduction / protein domain specific binding / focal adhesion / 中心体 / ubiquitin protein ligase binding / protein-containing complex / extracellular exosome / 生体膜 / 細胞膜 / 細胞質基質 / 細胞質 類似検索 - 分子機能 cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain / cAMP-dependent Protein Kinase, Chain A / cAMP-dependent protein kinase regulatory subunit / cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain / Regulatory subunit of type II PKA R-subunit / RIIalpha, Regulatory subunit portion of type II PKA R-subunit / Cyclic nucleotide-binding domain signature 2. / Cyclic nucleotide-binding domain signature 1. / Cyclic nucleotide-binding, conserved site / Cyclic nucleotide-monophosphate binding domain ... cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain / cAMP-dependent Protein Kinase, Chain A / cAMP-dependent protein kinase regulatory subunit / cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain / Regulatory subunit of type II PKA R-subunit / RIIalpha, Regulatory subunit portion of type II PKA R-subunit / Cyclic nucleotide-binding domain signature 2. / Cyclic nucleotide-binding domain signature 1. / Cyclic nucleotide-binding, conserved site / Cyclic nucleotide-monophosphate binding domain / Cyclic nucleotide-binding domain / cAMP/cGMP binding motif profile. / Cyclic nucleotide-binding domain / Cyclic nucleotide-binding domain superfamily / RmlC-like jelly roll fold / Up-down Bundle / Mainly Alpha 類似検索 - ドメイン・相同性 DITHIANE DIOL / cAMP-dependent protein kinase type II-alpha regulatory subunit 類似検索 - 構成要素生物種 HOMO SAPIENS (ヒト)SYNTHETIC CONSTRUCT (人工物) 手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 1.3 Å 詳細データ登録者 Gold, M.G. / Lygren, B. / Dokurno, P. / Hoshi, N. / McConnachie, G. / Tasken, K. / Carlson, C.R. / Scott, J.D. / Barford, D. 引用ジャーナル : Mol.Cell / 年 : 2006タイトル : Molecular Basis of Akap Specificity for Pka Regulatory Subunits.著者 : Gold, M.G. / Lygren, B. / Dokurno, P. / Hoshi, N. / Mcconnachie, G. / Tasken, K. / Carlson, C.R. / Scott, J.D. / Barford, D. 履歴 登録 2006年7月27日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2006年11月8日 Provider : repository / タイプ : Initial release改定 1.1 2017年2月8日 Group : Derived calculations / Non-polymer description ... Derived calculations / Non-polymer description / Other / Source and taxonomy / Structure summary / Version format compliance
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