登録情報 | データベース: PDB / ID: 6bzh |
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タイトル | Structure of mouse RIG-I tandem CARDs |
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要素 | Probable ATP-dependent RNA helicase DDX58 |
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キーワード | HYDROLASE / CARD RIG-I DEAD-box RNA Helicases |
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機能・相同性 | 機能・相同性情報
OAS antiviral response / Negative regulators of DDX58/IFIH1 signaling / ISG15 antiviral mechanism / RIG-I signaling pathway / positive regulation of myeloid dendritic cell cytokine production / detection of virus / Ub-specific processing proteases / positive regulation of response to cytokine stimulus / positive regulation of granulocyte macrophage colony-stimulating factor production / pattern recognition receptor activity ...OAS antiviral response / Negative regulators of DDX58/IFIH1 signaling / ISG15 antiviral mechanism / RIG-I signaling pathway / positive regulation of myeloid dendritic cell cytokine production / detection of virus / Ub-specific processing proteases / positive regulation of response to cytokine stimulus / positive regulation of granulocyte macrophage colony-stimulating factor production / pattern recognition receptor activity / cytoplasmic pattern recognition receptor signaling pathway / cellular response to exogenous dsRNA / response to exogenous dsRNA / positive regulation of interferon-alpha production / bicellular tight junction / antiviral innate immune response / positive regulation of defense response to virus by host / positive regulation of interferon-beta production / regulation of cell migration / positive regulation of interleukin-8 production / ruffle membrane / response to virus / positive regulation of interleukin-6 production / positive regulation of tumor necrosis factor production / double-stranded RNA binding / actin cytoskeleton / double-stranded DNA binding / gene expression / defense response to virus / RNA helicase activity / single-stranded RNA binding / RNA helicase / ribonucleoprotein complex / innate immune response / ubiquitin protein ligase binding / positive regulation of gene expression / GTP binding / positive regulation of transcription by RNA polymerase II / ATP hydrolysis activity / zinc ion binding / ATP binding / identical protein binding / cytoplasm / cytosol類似検索 - 分子機能 RIG-I, CARD domain repeat 2 / Death Domain, Fas / Death Domain, Fas / RIG-I-like receptor, C-terminal / RIG-I receptor C-terminal domain / RIG-I-like receptor, C-terminal regulatory domain / RIG-I-like receptor, C-terminal domain superfamily / C-terminal domain of RIG-I / RIG-I-like receptor (RLR) C-terminal regulatory (CTR) domain profile. / Caspase recruitment domain ...RIG-I, CARD domain repeat 2 / Death Domain, Fas / Death Domain, Fas / RIG-I-like receptor, C-terminal / RIG-I receptor C-terminal domain / RIG-I-like receptor, C-terminal regulatory domain / RIG-I-like receptor, C-terminal domain superfamily / C-terminal domain of RIG-I / RIG-I-like receptor (RLR) C-terminal regulatory (CTR) domain profile. / Caspase recruitment domain / Caspase recruitment domain / Death-like domain superfamily / DEAD/DEAH box helicase / DEAD/DEAH box helicase domain / Helicase conserved C-terminal domain / helicase superfamily c-terminal domain / Superfamilies 1 and 2 helicase C-terminal domain profile. / Superfamilies 1 and 2 helicase ATP-binding type-1 domain profile. / DEAD-like helicases superfamily / Helicase, C-terminal / Helicase superfamily 1/2, ATP-binding domain / P-loop containing nucleoside triphosphate hydrolase / Orthogonal Bundle / Mainly Alpha類似検索 - ドメイン・相同性 Antiviral innate immune response receptor RIG-I類似検索 - 構成要素 |
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生物種 | ![](img/tx_mammal.gif) Mus musculus (ハツカネズミ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.5 Å |
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データ登録者 | Kershaw, N.J. / D'Cruz, A.A. / Babon, J.J. / Nicholson, S.E. |
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資金援助 | オーストラリア, 1件 組織 | 認可番号 | 国 |
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National Heath and Medical Research Council | | オーストラリア |
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引用 | ジャーナル: Biochem. J. / 年: 2018 タイトル: Identification of a second binding site on the TRIM25 B30.2 domain. 著者: D'Cruz, A.A. / Kershaw, N.J. / Hayman, T.J. / Linossi, E.M. / Chiang, J.J. / Wang, M.K. / Dagley, L.F. / Kolesnik, T.B. / Zhang, J.G. / Masters, S.L. / Griffin, M.D.W. / Gack, M.U. / Murphy, ...著者: D'Cruz, A.A. / Kershaw, N.J. / Hayman, T.J. / Linossi, E.M. / Chiang, J.J. / Wang, M.K. / Dagley, L.F. / Kolesnik, T.B. / Zhang, J.G. / Masters, S.L. / Griffin, M.D.W. / Gack, M.U. / Murphy, J.M. / Nicola, N.A. / Babon, J.J. / Nicholson, S.E. |
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履歴 | 登録 | 2017年12月24日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2018年1月17日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2018年1月31日 | Group: Database references / カテゴリ: citation / citation_author Item: _citation.journal_volume / _citation.page_first ..._citation.journal_volume / _citation.page_first / _citation.page_last / _citation.year / _citation_author.name |
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改定 1.2 | 2023年10月4日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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