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-Structure paper
Title | Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs |
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Journal, issue, pages | Nat. Struct. Mol. Biol., Vol. 21, Page 803-809, Year 2014 |
Publish date | Jul 10, 2014 (structure data deposition date) |
Authors | Chamberlain, P.P. / Lopez-Girona, A. / Miller, K. / Carmel, G. / Pagarigan, B. / Chie-Leon, B. / Rychak, E. / Corral, L.G. / Ren, Y.J. / Wang, M. ...Chamberlain, P.P. / Lopez-Girona, A. / Miller, K. / Carmel, G. / Pagarigan, B. / Chie-Leon, B. / Rychak, E. / Corral, L.G. / Ren, Y.J. / Wang, M. / Riley, M. / Delker, S.L. / Ito, T. / Ando, H. / Mori, T. / Hirano, Y. / Handa, H. / Hakoshima, T. / Daniel, T.O. / Cathers, B.E. |
External links | Nat. Struct. Mol. Biol. / PubMed:25108355 |
Methods | X-ray diffraction |
Resolution | 1.93 - 2 Å |
Structure data | PDB-3wx1: PDB-3wx2: |
Chemicals | ChemComp-ZN: ChemComp-SO4: ChemComp-HOH: |
Source |
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Keywords | METAL BINDING PROTEIN / Zinc Finger / E3 ubiquitin ligase |