タイトル | Discovery and characterization of genes conferring natural resistance to the antituberculosis antibiotic capreomycin. |
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ジャーナル・号・ページ | Commun Biol, Vol. 6, Page 1282-1282, Year 2023 |
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掲載日 | 2023年2月2日 (構造データの登録日) |
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著者 | Toh, S.I. / Elaine Keisha, J. / Wang, Y.L. / Pan, Y.C. / Jhu, Y.H. / Hsiao, P.Y. / Liao, W.T. / Chen, P.Y. / Ko, T.M. / Chang, C.Y. |
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リンク | Commun Biol / PubMed:38114770 |
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手法 | X線回折 |
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解像度 | 1.95 - 3 Å |
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構造データ | PDB-8i80: Crystal structure of Cph001-D189N 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-8i82: Crystal structure of Cph001-D189N in complex with CMN IIA 手法: X-RAY DIFFRACTION / 解像度: 1.95 Å PDB-8i84: Crystal structure of Cph001-D189N in complex with CMN IIB 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-8i85: Crystal structure of Cph001-D189N in complex with ATP 手法: X-RAY DIFFRACTION / 解像度: 2.17 Å PDB-8i86: Crystal structure of Cph001-D189N in complex with GTP 手法: X-RAY DIFFRACTION / 解像度: 2.23 Å PDB-8i89: Crystal structure of Cph001-D189N in complex with VIO 手法: X-RAY DIFFRACTION / 解像度: 2 Å PDB-8i8g: Crystal structure of Cph001-D189N in complex with CMN IIA and ATP 手法: X-RAY DIFFRACTION / 解像度: 3 Å PDB-8i8h: Crystal structure of Cph001-D189N in complex with VIO and ATP 手法: X-RAY DIFFRACTION / 解像度: 2.02 Å |
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化合物 | |
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由来 | streptosporangium roseum (バクテリア) saccharothrix mutabilis subsp. capreolus (バクテリア) streptomyces vinaceus (バクテリア)
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キーワード | TRANSFERASE / Phosphotransferase / Capreomycin / Cph / Resistance / ATP / GTP / Viomycin |
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