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-Structure paper
Title | Discovery of 4,5,6,7-Tetrahydropyrazolo[1.5-a]pyrizine Derivatives as Core Protein Allosteric Modulators (CpAMs) for the Inhibition of Hepatitis B Virus. |
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Journal, issue, pages | J. Med. Chem., Vol. 66, Page 14116-14132, Year 2023 |
Publish date | Aug 22, 2023 (structure data deposition date) |
![]() | Kou, B. / Zhang, Z. / Han, X. / Zhou, Z. / Xu, Z. / Zhou, X. / Shen, F. / Zhou, Y. / Tian, X. / Yang, G. ...Kou, B. / Zhang, Z. / Han, X. / Zhou, Z. / Xu, Z. / Zhou, X. / Shen, F. / Zhou, Y. / Tian, X. / Yang, G. / Young, J.A.T. / Qiu, H. / Ottaviani, G. / Mayweg, A. / Zhu, W. / Shen, H.C. / Liu, H. / Hu, T. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | ![]() PDB-8khu: |
Chemicals | ![]() ChemComp-IPA: ![]() ChemComp-VX0: ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
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![]() | VIRAL PROTEIN / HBV capsid assembly mudulator / ANTIVIRAL PROTEIN |