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-Structure paper
Title | Design, synthesis and pharmacological characterization of N-(3-ethylbenzo[d]isoxazol-5-yl) sulfonamide derivatives as BRD4 inhibitors against acute myeloid leukemia. |
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Journal, issue, pages | Acta Pharmacol. Sin., Vol. 43, Page 2735-2748, Year 2022 |
Publish date | Aug 6, 2021 (structure data deposition date) |
![]() | Zhang, M.F. / Luo, X.Y. / Zhang, C. / Wang, C. / Wu, X.S. / Xiang, Q.P. / Xu, Y. / Zhang, Y. |
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Methods | X-ray diffraction |
Resolution | 1.82 - 2.24 Å |
Structure data | ![]() PDB-7v1u: ![]() PDB-7v2j: |
Chemicals | ![]() ChemComp-5E3: ![]() ChemComp-EDO: ![]() ChemComp-HOH: ![]() ChemComp-5FZ: |
Source |
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![]() | PROTEIN BINDING / BRD4(1) / Bromodomain |