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-Structure paper
Title | Down-regulation of NF-kappa B transcriptional activity in HIV-associated kidney disease by BRD4 inhibition. |
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Journal, issue, pages | J. Biol. Chem., Vol. 287, Page 28840-28851, Year 2012 |
Publish date | May 3, 2012 (structure data deposition date) |
![]() | Zhang, G. / Liu, R. / Zhong, Y. / Plotnikov, A.N. / Zhang, W. / Zeng, L. / Rusinova, E. / Gerona-Nevarro, G. / Moshkina, N. / Joshua, J. ...Zhang, G. / Liu, R. / Zhong, Y. / Plotnikov, A.N. / Zhang, W. / Zeng, L. / Rusinova, E. / Gerona-Nevarro, G. / Moshkina, N. / Joshua, J. / Chuang, P.Y. / Ohlmeyer, M. / He, J.C. / Zhou, M.M. |
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Methods | NMR (solution) / X-ray diffraction |
Resolution | 1.4 Å |
Structure data | ![]() PDB-2lsp: ![]() PDB-4f3i: |
Chemicals | ![]() ChemComp-EDO: ![]() ChemComp-0S6: ![]() ChemComp-HOH: |
Source |
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![]() | PROTEIN BINDING / NF-kB / BRD4 / HIV / bromodomain / kidney disease / SIGNALING PROTEIN/INHIBITOR / protein-inhibitor complex / acetyl-lysine binding / nucleus / SIGNALING PROTEIN-INHIBITOR complex |