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Structure paper

TitleLigand Binding Domain
Journal, issue, pagesTo Be Published
Publish dateJan 8, 2020 (structure data deposition date)
AuthorsFanning, S.W.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-6vgh:
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant In Complex with Lasofoxifene
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-C3D:
(5R,6S)-6-PHENYL-5-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]-5,6,7,8-TETRAHYDRONAPHTHALEN-2-OL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Breast Cancer / Steroid Receptor / Activating Mutant / Selective Estrogen Receptor Modulator / Antiestrogen / Lasofoxifene

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