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Titlecryo-EM structure of M1 muscarinic acetylcholine receptor-alpha5 helix of G11 protein complex bound to iperoxo and nanobody Nb1B4
Journal, issue, pagesTo Be Published
Publish dateApr 5, 2025 (structure data deposition date)
AuthorsZhang X / Gao K / Liu X
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.88 Å
Structure data

64050

9ucp

EMDB-64050, PDB-9ucp:
cryo-EM structure of M1 muscarinic acetylcholine receptor-alpha5 helix of G11 protein complex bound to iperoxo and nanobody Nb1B4
Method: EM (single particle) / Resolution: 2.88 Å

Chemicals

ChemComp-IXO:
4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium

Source
  • homo sapiens (human)
  • vicugna pacos (alpaca)
KeywordsMEMBRANE PROTEIN/IMMUNE SYSTEM / GPCR / active-state / nanobody / de novo protein / MEMBRANE PROTEIN-IMMUNE SYSTEM complex

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