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TitleStructural mechanisms of pump assembly and drug transport in the AcrAB-TolC efflux system
Journal, issue, pagesBiorxiv, Year 2025
Publish dateMay 25, 2025 (structure data deposition date)
AuthorsGe X / Gu Z / Wang J
External linksBiorxiv / Search PubMed
MethodsEM (single particle)
Resolution3.26 - 3.56 Å
Structure data

64784

9v52

EMDB-64784, PDB-9v52:
Structure of TolC and YbjP closed state complex
Method: EM (single particle) / Resolution: 3.56 Å

64785

9v53

EMDB-64785, PDB-9v53:
Structure of TolC, YbjP, and AcrABZ complex
Method: EM (single particle) / Resolution: 3.39 Å

64787

9v55

EMDB-64787, PDB-9v55:
Structure of TolC, YbjP, and AcrA complex
Method: EM (single particle) / Resolution: 3.26 Å

Source
  • Escherichia coli (E. coli)
  • escherichia coli (strain k12) (bacteria)
  • escherichia coli k-12 (bacteria)
KeywordsPROTEIN TRANSPORT / Multidrug efflux pump / TolC / YbjP / AcrA / AcrB / lipoprotein / antibiotic resistance / Gram-negative

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