EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Expanding the molecular landscape of fragments binding to trypanothione reductase, a legitimate target for drug design against human African trypanosomiasis
ジャーナル・号・ページ	Front Chem Biol, Vol. Volume 4 - 2025, Year 2025
掲載日	2025年2月18日 (構造データの登録日)
著者	Exertier, C. / Antonelli, L. / Brufani, V. / Colotti, G. / Ilari, A. / Fiorillo, A.
リンク	Front Chem Biol / PubMedで検索
手法	X線回折
解像度	1.62 - 2.11 Å
構造データ	PDB-9ife: PANDDA analysis - Crystal structure of Trypanosoma brucei trypanothione reductase in complex with Z943693514 手法: X-RAY DIFFRACTION / 解像度: 1.68 Å PDB-9iff: PANDDA analysis - Crystal structure of Trypanosoma brucei trypanothione reductase in complex with Z2856434836 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-9ifg: PANDDA analysis - Crystal structure of Trypanosoma brucei trypanothione reductase in complex with Z2204875953 手法: X-RAY DIFFRACTION / 解像度: 1.86 Å PDB-9ifh: PANDDA analysis - Crystal structure of Trypanosoma brucei trypanothione reductase in complex with Z2856434890 手法: X-RAY DIFFRACTION / 解像度: 1.73 Å PDB-9ifi: PANDDA analysis - Crystal structure of Trypanosoma brucei trypanothione reductase in complex with Z32399802 手法: X-RAY DIFFRACTION / 解像度: 1.67 Å PDB-9ifj: PANDDA analysis - Crystal structure of Trypanosoma brucei trypanothione reductase in complex with Z2017861827 手法: X-RAY DIFFRACTION / 解像度: 1.62 Å PDB-9ifl: PANDDA analysis - Crystal structure of Trypanosoma brucei trypanothione reductase in complex with Z319545618 手法: X-RAY DIFFRACTION / 解像度: 1.71 Å PDB-9ifn: PANDDA analysis - Crystal structure of Trypanosoma brucei trypanothione reductase in complex with Z436190540 手法: X-RAY DIFFRACTION / 解像度: 2.11 Å
化合物	ChemComp-FAD: FLAVIN-ADENINE DINUCLEOTIDE / FADYM ChemComp-IMD: IMIDAZOLE ChemComp-PEG: DI(HYDROXYETHYL)ETHER ChemComp-DMS: DIMETHYL SULFOXIDE / DMSO, 沈殿剤YM ChemComp-BR: BROMIDE ION ChemComp-NA: Unknown entry ChemComp-GT4: ~{N}-(4-hydroxyphenyl)-2-methoxy-ethanamide ChemComp-HOH: WATER ChemComp-LPZ: 2-(4-methylphenoxy)-1-(4-methylpiperazin-4-ium-1-yl)ethanone ChemComp-Q7L: (3P)-3-(2H-1,3-benzodioxol-5-yl)-1H-pyrazole ChemComp-NZD: 4-methyl-N-phenylpiperazine-1-carboxamide PDB-1i3u: THREE-DIMENSIONAL STRUCTURE OF A LLAMA VHH DOMAIN COMPLEXED WITH THE DYE RR1 PDB-1be9: THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM CRIPT. ChemComp-RXS: 3-[(2-methyl-1H-imidazol-1-yl)methyl]benzonitrile PDB-1i3v: THREE-DIMENSIONAL STRUCTURE OF A LAMA VHH DOMAIN UNLIGANDED
由来	trypanosoma brucei (トリパノソーマ)
キーワード	OXIDOREDUCTASE / trypanothione reductase