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TitleCrystal Structure of a Dihydroxycoumarin RNase H Active-Site Inhibitor in Complex with HIV-1 Reverse Transcriptase
Journal, issue, pagesTo Be Published
Publish dateDec 31, 2015 (structure data deposition date)
AuthorsKirby, K.A. / Sarafianos, S.G.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution3.043 Å
Structure data

PDB-5hbm:
Crystal Structure of a Dihydroxycoumarin RNase H Active-Site Inhibitor in Complex with HIV-1 Reverse Transcriptase
Method: X-RAY DIFFRACTION / Resolution: 3.043 Å

Chemicals

ChemComp-NVP:
11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE / medication*YM

ChemComp-F95:
(7,8-dihydroxy-2-oxo-2H-chromen-4-yl)acetic acid

ChemComp-MN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus type 1 bh10
KeywordsTRANSFERASE / HYDROLASE/INHIBITOR / HYDROLASE / INHIBITOR / HYDROLASE-INHIBITOR complex

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