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Structure paper

TitleSF2312, a natural phosphonate inhibitor of Enolase
Journal, issue, pagesTo be Published
Publish dateNov 18, 2015 (structure data deposition date)
AuthorsLeonard, P.G. / Maxwell, D. / Satani, N. / Peng, Z. / Link, T. / Lee, G. / Bosajou, A. / Sun, D. / Lin, Y.E. / DiFrancesco, M.E. ...Leonard, P.G. / Maxwell, D. / Satani, N. / Peng, Z. / Link, T. / Lee, G. / Bosajou, A. / Sun, D. / Lin, Y.E. / DiFrancesco, M.E. / Czako, B. / Wang, Y.A. / Bornmann, W. / DePhinho, R.A. / Muller, F.L.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.047 Å
Structure data

PDB-5eu9:
Structure of Human Enolase 2 in complex with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid
Method: X-RAY DIFFRACTION / Resolution: 2.047 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-5TX:
((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLYASE/LYASE INHIBITOR / enolase gamma / glycolysis / neuron specific enolase / carbohydrate metabolism / LYASE-LYASE INHIBITOR complex

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