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TitleMAT2A in complex with SAM and allosteric inhibitor SCR-7952
Journal, issue, pagesTo Be Published
Publish dateDec 20, 2023 (structure data deposition date)
AuthorsZhou F
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.16 Å
Structure data

38392

8xj2

EMDB-38392, PDB-8xj2:
MAT2A in complex with SAM and allosteric inhibitor SCR-7952
Method: EM (single particle) / Resolution: 3.16 Å

Chemicals

PDB-1lvl:
THE REFINED STRUCTURE OF PSEUDOMONAS PUTIDA LIPOAMIDE DEHYDROGENASE COMPLEXED WITH NAD+ AT 2.45 ANGSTROMS RESOLUTION

ChemComp-SAM:
S-ADENOSYLMETHIONINE

Source
  • homo sapiens (human)
KeywordsANTITUMOR PROTEIN / methionine adenosyltransferase / cancer / SAM

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