EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	The stereospecific activities of the tetrahydroprotoberberine N-methyltransferase with alternative substrates provide insight into the catalytic mechanisms of benzylisoquinoline alkaloid N-methylation.
ジャーナル・号・ページ	To Be Published
掲載日	2024年9月2日 (構造データの登録日)
著者	Lang, D.E. / Ng, K.K.S. / Rehman, F. / Morris, J.S. / Facchini, P.J.
リンク	PubMedで検索
手法	X線回折
解像度	1.6 - 2.5 Å
構造データ	PDB-9dg6: Tetrahydroprotoberberine N-methyltransferase complex with N-methylcanadine and SAH 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-9dg7: Tetrahydroprotoberberine N-methyltransferase E204A mutant in complex with R-reticuline and SAM 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å PDB-9dg8: Tetrahydroprotoberberine N-methyltransferase E204A mutant in complex with (S)-reticuline and SAM 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-9dg9: Tetrahydroprotoberberine N-methyltransferase E207A mutant in complex with R-reticuline and SAM 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-9dga: Tetrahydroprotoberberine N-methyltransferase in complex with (R)-reticuline and SAM 手法: X-RAY DIFFRACTION / 解像度: 2 Å PDB-9dgb: Tetrahydroprotoberberine N-methyltransferase in complex with (S)-reticuline and SAM 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-9dgc: Tetrahydroprotoberberine N-methyltransferase E207A mutant in complex with (S)-reticuline and SAM 手法: X-RAY DIFFRACTION / 解像度: 2 Å PDB-9dgd: Tetrahydroprotoberberine N-methyltransferase in complex with boldine and SAH 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-9dge: Tetrahydroprotoberberine N-methyltransferase product complex with dextromethorphan and SAM 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-9dgf: Tetrahydroprotoberberine N-methyltransferase product complex with N-methyltetrahydropalmatine and SAH 手法: X-RAY DIFFRACTION / 解像度: 1.85 Å
化合物	ChemComp-SAH: S-ADENOSYL-L-HOMOCYSTEINE PDB-1a4i: HUMAN TETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE ChemComp-SO4: SULFATE ION ChemComp-HOH: WATER ChemComp-SAM: S-ADENOSYLMETHIONINE PDB-1a4h: STRUCTURE OF THE N-TERMINAL DOMAIN OF THE YEAST HSP90 CHAPERONE IN COMPLEX WITH GELDANAMYCIN ChemComp-REN: (S)-reticuline ChemComp-GOL: GLYCEROL ChemComp-CL: Unknown entry ChemComp-GHT: Boldine 化合物画像なし ChemComp-4NQ: Unknown entry PDB-1a4j: DIELS ALDER CATALYTIC ANTIBODY GERMLINE PRECURSOR
由来	glaucium flavum (植物)
キーワード	TRANSFERASE / methyltransferase / benzylisoquinoline alkaloid