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Structure paper

TitleCryo-EM structure of a mitochondrial calcium uniporter.
Journal, issue, pagesScience, Vol. 361, Issue 6401, Page 506-511, Year 2018
Publish dateAug 3, 2018
AuthorsJiho Yoo / Mengyu Wu / Ying Yin / Mark A Herzik / Gabriel C Lander / Seok-Yong Lee
External linksPubMed:29954988 / Publisher's page
KeywordsAmino Acid Motifs / Calcium / Calcium Channels / Conserved Sequence / Cryoelectron Microscopy / Fungal Proteins / Models, Chemical / Mutagenesis / Neurospora crassa / Protein Conformation / Protein Multimerization / mitochondrial calcium uniporter / TRANSPORT PROTEIN / calcium-selective ion channel / calcium uptake / uniporter
MethodsEM (single particle)
Resolution3.7 A
Structure data

EMDB-8911:
Cryo-EM structure of a mitochondrial calcium uniporter

PDB-6dt0:
Cryo-EM structure of a mitochondrial calcium uniporter

Chemicals

ChemComp-CA:
CALCIUM IONCalcium

Source
  • Neurospora crassa (fungus)
  • neurospora crassa (fungus)

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Feb 20, 2018. PDBj/BINDS workshop in Osaka University

PDBj/BINDS workshop in Osaka University

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    Oct 4, 2017. Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

    Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

    • Jacques Dubochet (University of Lausanne, Switzerland) is a pioneer of ice-embedding method of EM specimen (as known as cryo-EM), Most of 3DEM structures in EMDB and PDB are obtained using his method.
    • Joachim Frank (Columbia University, New York, USA) is a pioneer of single particle reconstruction, which is the most used reconstruction method for 3DEM structures in EMDB and EM entries in PDB. And also, he is a develper of Spider, which is one of the most famous software in this field, and is used for some EM Navigor data (e.g. map projection/slice images).
    • Richard Henderson (MRC Laboratory of Molecular Biology, Cambridge, UK) was determined the first biomolecule structure by EM. The first EM entry in PDB, PDB-1brd is determinedby him.

    External links: The 2017 Nobel Prize in Chemistry - Press Release

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    Jul 12, 2017. Major update of PDB

    Major update of PDB

    • wwPDB released updated PDB data conforming to the new PDBx/mmCIF dictionary. This is a major update changing the version number from 4 to 5, and with Remediation, in which all the entries are updated. See below links for details.
    • In this update, many items about electron microscopy experimental information are reorganized (e.g. em_software). Now, EM Navigator and Yorodumi are based on the updated data.

    External links: wwPDB Remediation / Enriched Model Files Conforming to OneDep Data Standards Now Available in the PDB FTP Archive

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    Sep 15, 2016. EM Navigator & Yorodumi renewed

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    EMN Papers

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