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Structure paper

TitleStructure of a eukaryotic voltage-gated sodium channel at near-atomic resolution.
Journal, issue, pagesScience, Vol. 355, Issue 6328, Year 2017
Publish dateMar 3, 2017
AuthorsHuaizong Shen / Qiang Zhou / Xiaojing Pan / Zhangqiang Li / Jianping Wu / Nieng Yan
External linksPubMed:28183995 / Publisher's page
MethodsEM (single particle)
Resolution3.8 A
Structure data

EMDB-6698:
Structure of a eukaryotic voltage-gated sodium channel at near atomic resolution

PDB-5x0m:
Structure of a eukaryotic voltage-gated sodium channel at near atomic resolution

Chemicals

ChemComp-NAG:
N-ACETYL-D-GLUCOSAMINE

ChemComp-BMA:
BETA-D-MANNOSE

SourcePeriplaneta americana / arthropod / ワモンゴキブリ
KeywordsAnimals / Conserved Sequence / Cryoelectron Microscopy / Glycosylation / Large-Conductance Calcium-Activated Potassium Channel alpha Subunits / Models, Chemical / Periplaneta / Protein Domains / Voltage-Gated Sodium Channels / MEMBRANE PROTEIN / ion channel / membrane protein

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Oct 4, 2017. Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

  • Jacques Dubochet (University of Lausanne, Switzerland) is a pioneer of ice-embedding method of EM specimen (as known as cryo-EM), Most of 3DEM structures in EMDB and PDB are obtained using his method.
  • Joachim Frank (Columbia University, New York, USA) is a pioneer of single particle reconstruction, which is the most used reconstruction method for 3DEM structures in EMDB and EM entries in PDB. And also, he is a develper of Spider, which is one of the most famous software in this field, and is used for some EM Navigor data (e.g. map projection/slice images).
  • Richard Henderson (MRC Laboratory of Molecular Biology, Cambridge, UK) was determined the first biomolecule structure by EM. The first EM entry in PDB, PDB-1brd is determinedby him.

External links: The 2017 Nobel Prize in Chemistry - Press Release

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Jul 12, 2017. Major update of PDB

Major update of PDB

  • wwPDB released updated PDB data conforming to the new PDBx/mmCIF dictionary. This is a major update changing the version number from 4 to 5, and with Remediation, in which all the entries are updated. See below links for details.
  • In this update, many items about electron microscopy experimental information are reorganized (e.g. em_software). Now, EM Navigator and Yorodumi are based on the updated data.

External links: wwPDB Remediation / Enriched Model Files Conforming to OneDep Data Standards Now Available in the PDB FTP Archive

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Omokage search with filter

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EM Navigator & Yorodumi renewed

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Related info.: Changes in new EM Navigator and Yorodumi / EM Navigator (legacy version) / Yorodumi (legacy version)

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Aug 31, 2016. New EM Navigator & Yorodumi

New EM Navigator & Yorodumi

  • In 15th Sep 2016, the development versions of EM Navigator and Yorodumi will replace the official versions.
  • Current version will continue as 'legacy version' for some time.

Related info.: Changes in new EM Navigator and Yorodumi / EM Navigator / Yorodumi / EM Navigator (legacy version) / Yorodumi (legacy version)

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EMN Papers

Database of articles cited by 3DEM data entries

  • Database of articles cited by 3DEM data entries in EMDB and PDB
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