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Structure paper

TitleStructure of a spliceosome remodelled for exon ligation.
Journal, issue, pagesNature, Vol. 542, Issue 7641, Page 377-380, Year 2017
Publish date2017--16
AuthorsSebastian M Fica / Chris Oubridge / Wojciech P Galej / Max E Wilkinson / Xiao-Chen Bai / Andrew J Newman / Kiyoshi Nagai
External linksPubMed:28076345 / Publisher's page
MethodsEM (single particle)
Resolution3.85 - 4.6 A
Structure data

EMDB-3539:
Structure of a spliceosome remodeled for exon ligation

EMDB-3541:
Structure of a spliceosome remodeled for exon ligation

EMDB-3542:
Structure of a spliceosome remodeled for exon ligation

PDB-5mps:
Structure of a spliceosome remodeled for exon ligation

PDB-5mq0:
Structure of a spliceosome remodeled for exon ligation

Chemicals

ChemComp-MG:
MAGNESIUM ION

ChemComp-K:
POTASSIUM ION

ChemComp-I6P:
INOSITOL 1,2,3,4,5,6-HEXAKISPHOSPHATE

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE

ChemComp-ZN:
ZINC ION

SourceSaccharomyces cerevisiae / yeast / サッカロミセス・セレビシエ /
KeywordsAdenosine / Adenosine Triphosphatases / Biocatalysis / CDC40 protein, S cerevisiae / CEF1 protein, S cerevisiae / Catalytic Domain / Cell Cycle Proteins / Cryoelectron Microscopy / DEAD-box RNA Helicases / DNA-Binding Proteins / Exons / PRP16 protein, S cerevisiae / PRP18 protein, S cerevisiae / PRP22 protein, S cerevisiae / PRP8 protein, S cerevisiae / Protein Binding / Protein Domains / RNA Helicases / RNA Splice Sites / RNA Splicing / RNA Splicing Factors / RNA, Small Nuclear / RNA-Binding Proteins / Ribonuclease H / Ribonucleoprotein, U4-U6 Small Nuclear / Ribonucleoprotein, U5 Small Nuclear / Ribonucleoproteins, Small Nuclear / SLU7 protein, S cerevisiae / Saccharomyces cerevisiae / Saccharomyces cerevisiae Proteins / Spliceosomes / U6 small nuclear RNA / SPLICING / pre-mRNA splicing / trans-esterification / lariat intermediate / complex C-star / Splicing

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