|Title||Structural Basis of RNA Polymerase I Transcription Initiation.|
|Journal, issue, pages||Cell, Vol. 169, Issue 1, Page 120-131.e22, Year 2017|
|Publish date||Mar 23, 2017|
|Authors||Christoph Engel / Tobias Gubbey / Simon Neyer / Sarah Sainsbury / Christiane Oberthuer / Carlo Baejen / Carrie Bernecky / Patrick Cramer|
|External links||PubMed:28340337 / Publisher's page|
|Keywords||Cryoelectron Microscopy / Crystallography, X-Ray / Models, Molecular / Multiprotein Complexes / Promoter Regions, Genetic / RNA Polymerase I / Saccharomyces cerevisiae / Saccharomyces cerevisiae Proteins / Transcription Initiation, Genetic / Transcription, Genetic / TRANSCRIPTION / Transcription / RNA polymerase I initiation / TRANSFERASE / Transferase / RNA polymerase I / initially transcribing complex / transferase / RNA POLYMERASE I INITIATION / CORE FACTOR|
|Methods||EM (single particle) / X-ray diffraction|
|Resolution||3.2 - 7.7 A|
+About EMN Papers
-Feb 20, 2018. PDBj/BINDS workshop in Osaka University
PDBj/BINDS workshop in Osaka University
-Oct 4, 2017. Three pioneers of this field were awarded Nobel Prize in Chemistry 2017
Three pioneers of this field were awarded Nobel Prize in Chemistry 2017
- Jacques Dubochet (University of Lausanne, Switzerland) is a pioneer of ice-embedding method of EM specimen (as known as cryo-EM), Most of 3DEM structures in EMDB and PDB are obtained using his method.
- Joachim Frank (Columbia University, New York, USA) is a pioneer of single particle reconstruction, which is the most used reconstruction method for 3DEM structures in EMDB and EM entries in PDB. And also, he is a develper of Spider, which is one of the most famous software in this field, and is used for some EM Navigor data (e.g. map projection/slice images).
- Richard Henderson (MRC Laboratory of Molecular Biology, Cambridge, UK) was determined the first biomolecule structure by EM. The first EM entry in PDB, PDB-1brd is determinedby him.
External links: The 2017 Nobel Prize in Chemistry - Press Release
+Jul 12, 2017. Major update of PDB
Major update of PDB
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+Jun 16, 2017. Omokage search with filter
Omokage search with filter
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Related info.: EMDB / PDB / Q: What is the data source of EM Navigator? / EM Navigator / Yorodumi Papers / Changes in new EM Navigator and Yorodumi