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Showing 1 - 50 of 84 items for author: y. & zhang

PDB-5m50:
Mechanism of microtubule minus-end recognition and protection by CAMSAP proteins
Method: single particle / : Akhmanova A, Moores CA, Baldus M, Steinmetz MO, Topf M, Roberts AJ, Grant BJ, Scarabelli G, Joseph AP, van Hooff JJE, Houben K, Hua S, Luo Y, Stangier MM, Jiang K, Atherton J

PDB-5m54:
Mechanism of microtubule minus-end recognition and protection by CAMSAP proteins
Method: single particle / : Akhmanova A, Moores CA, Baldus M, Steinmetz MO, Topf M, Roberts AJ, Grant BJ, Scarabelli G, Joseph AJ, van Hooff JJE, Houben K, Hua S, Luo Y, Stangier MM, Jiang K, Atherton J

PDB-5m5c:
Mechanism of microtubule minus-end recognition and protection by CAMSAP proteins
Method: single particle / : Akhmanova A, Moores CA, Baldus M, Steinmetz MO, Topf M, Roberts AJ, Grant BJ, Scarabelli G, Joseph AP, van Hooff JJE, Houben K, Hua S, Luo Y, Stangier MM, Jiang K, Atherton J

PDB-5xym:
Large subunit of Mycobacterium smegmatis
Method: single particle / : Li Z, Ge X, Zhang Y, Zheng L, Sanyal S, Gao N

PDB-5xyu:
Small subunit of Mycobacterium smegmatis ribosome
Method: single particle / : Li Z, Zhang Y, Zheng L, Ge X, Sanyal S, Gao N

PDB-5v7q:
Cryo-EM structure of the large ribosomal subunit from Mycobacterium tuberculosis bound with a potent linezolid analog
Method: single particle / : Yang K, Chang JY, Cui Z, Zhang J

PDB-5v93:
Cryo-EM structure of the 70S ribosome from Mycobacterium tuberculosis bound with Capreomycin
Method: single particle / : Yang K, Chang JY, Cui Z, Li X, Meng R, Duan L, Thongchol J, Jakana J, Huwe C, Sacchettini J, Zhang J

PDB-5xwy:
Electron cryo-microscopy structure of LbuCas13a-crRNA binary complex
Method: single particle / : Zhang X, Wang Y, Ma J, Liu L, Li X, Li Z, You L, Wang J, Wang M

PDB-5xjc:
Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom
Method: single particle / : Zhang X, Yan C, Hang J, Finci IL, Lei J, Shi Y

PDB-5vkq:
Structure of a mechanotransduction ion channel Drosophila NOMPC in nanodisc
Method: single particle / : Jin P, Bulkley D, Guo Y, Zhang W, Guo Z, Huynh W, Wu S, Meltzer S, Chen T, Jan LY, Jan YN, Cheng Y

PDB-5vai:
Cryo-EM structure of the activated Glucagon-like peptide-1 receptor in complex with G protein
Method: single particle / : Zhang Y, Sun B, Feng D, Hu H, Chu M, Qu Q, Tarrasch JT, Li S, Kobilka TS, Kobilka BK, Skiniotis G

PDB-5uz7:
Volta phase plate cryo-electron microscopy structure of a calcitonin receptor-heterotrimeric Gs protein complex
Method: single particle / : Liang YL, Khoshouei M, Radjainia M, Zhang Y, Glukhova A, Tarrasch J, Thal DM, Furness SGB, Christopoulos G, Coudrat T, Danev R, Baumeister W, Miller LJ, Christopoulos A, Kobilka BK, Wootten D, Skiniotis G, Sexton PM

PDB-5x58:
Prefusion structure of SARS-CoV spike glycoprotein, conformation 1
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x59:
Prefusion structure of MERS-CoV spike glycoprotein, three-fold symmetry
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x5b:
Prefusion structure of SARS-CoV spike glycoprotein, conformation 2
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x5c:
Prefusion structure of MERS-CoV spike glycoprotein, conformation 1
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x5f:
Prefusion structure of MERS-CoV spike glycoprotein, conformation 2
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5wvi:
The resting state of yeast proteasome
Method: single particle / : Ding Z, Cong Y

PDB-5wvk:
Yeast proteasome-ADP-AlFx
Method: single particle / : Ding Z, Cong Y

PDB-5u0p:
Cryo-EM structure of the transcriptional Mediator
Method: single particle / : Tsai KL, Yu X, Gopalan S, Chao TC, Zhang Y, Florens L, Washburn MP, Murakami K, Conaway RC, Conaway JW, Asturias F

PDB-5u0s:
Cryo-EM structure of the Mediator-RNAPII complex
Method: single particle / : Tsai KL, Yu X, Gopalan S, Chao TC, Zhang Y, Florens L, Washburn MP, Murakami K, Conaway RC, Conaway JW, Asturias F

PDB-5wte:
Cryo-EM structure for Hepatitis A virus full particle
Method: single particle / : Wang X, Zhu L, Dang M, Hu Z, Gao Q, Yuan S, Sun Y, Zhang B, Ren J, Walter TS, Wang J, Fry EE, Stuart DI, Rao Z

PDB-5wtf:
Cryo-EM structure for Hepatitis A virus empty particle
Method: single particle / : Wang X, Zhu L, Dang M, Hu Z, Gao Q, Yuan S, Sun Y, Zhang B, Ren J, Walter TS, Wang J, Fry EE, Stuart DI, Rao Z

PDB-5wth:
Cryo-EM structure for Hepatitis A virus complexed with FAB
Method: single particle / : Wang X, Zhu L, Dang M, Hu Z, Gao Q, Yuan S, Sun Y, Zhang B, Ren J, Walter TS, Wang J, Fry EE, Stuart DI, Rao Z

PDB-5gzr:
Zika virus E protein complexed with a neutralizing antibody Z23-Fab
Method: single particle / : Gao GG, Shi Y, Peng R, Liu S

PDB-5h37:
Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0
Method: single particle / : Zhang S, Kostyuchenko V, Ng TS, Lim XN, Ooi JSG, Lambert S, Tan TY, Widman D, Shi J, Baric RS, Lok SM

PDB-3jbz:
Crystal structure of mTOR docked into EM map of dimeric ATM kinase
Method: single particle / : Lau WCY

PDB-3jbm:
Electron cryo-microscopy of a virus-like particle of orange-spotted grouper nervous necrosis virus
Method: single particle / : Xie J, Li K, Gao Y, Huang R, Lai Y, Shi Y, Yang S, Zhu G, Zhang Q, He J

PDB-5kc2:
Negative stain structure of Vps15/Vps34 complex
Method: single particle / : Kirsten ML, Zhang L, Ohashi Y, Perisic O, Williams RL, Sachse C

PDB-5kps:
Structure of RelA bound to ribosome in absence of A/R tRNA (Structure I)
Method: single particle / : Loveland AB, Bah E, Madireddy R, Zhang Y, Brilot AF, Grigorieff N, Korostelev AA

PDB-5kpv:
Structure of RelA bound to ribosome in presence of A/R tRNA (Structure II)
Method: single particle / : Loveland AB, Bah E, Madireddy R, Zhang Y, Brilot AF, Grigorieff N, Korostelev AA

PDB-5kpw:
Structure of RelA bound to ribosome in presence of A/R tRNA (Structure III)
Method: single particle / : Loveland AB, Bah E, Madireddy R, Zhang Y, Brilot AF, Grigorieff N, Korostelev AA

PDB-5kpx:
Structure of RelA bound to ribosome in presence of A/R tRNA (Structure IV)
Method: single particle / : Loveland AB, Bah E, Madireddy R, Zhang Y, Brilot AF, Grigorieff N, Korostelev AA

PDB-5gqh:
Cryo-EM structure of PaeCas3-AcrF3 complex
Method: single particle / : Zhang X, Ma J, Wang Y, Wang J

PDB-3jcs:
2.8 Angstrom cryo-EM structure of the large ribosomal subunit from the eukaryotic parasite Leishmania
Method: single particle / : Shalev-Benami M, Zhang Y, Matzov D, Halfon Y, Zackay A, Rozenberg H, Zimmerman E, Bashan A, Jaffe CL, Yonath A, Skiniotis G

PDB-3jb8:
Insight into Three-dimensional structure of Maize Chlorotic Mottle Virus Revealed by Single Particle Analysis
Method: single particle / : Wang CY, Zhang QF, Gao YZ, Zhou XP, Ji G, Huang XJ, Hong J, Zhang CX

PDB-3jct:
Cryo-em structure of eukaryotic pre-60S ribosomal subunits
Method: single particle / : Wu S, Kumcuoglu B, Yan KG, Brown H, Zhang YX, Tan D, Gamalinda M, Yuan Y, Li ZF, Jakovljevic J, Ma CY, Lei JL, Dong MQ, Woolford Jr JL, Gao N

PDB-3jcu:
Cryo-EM structure of spinach PSII-LHCII supercomplex at 3.2 Angstrom resolution
Method: single particle / : Wei XP, Zhang XZ, Su XD, Cao P, Liu XY, Li M, Chang WR, Liu ZF

PDB-5jb1:
Pseudo-atomic structure of Human Papillomavirus Type 59 L1 Virus-like Particle
Method: single particle / : Li ZH, Yan XD, Yu H, Zheng QB, Gu Y, Li SW

PDB-3jau:
The cryoEM map of EV71 mature viron in complex with the Fab fragment of antibody D5
Method: single particle / : Fan C, Ye XH, Ku ZQ, Zuo T, Kong LL, Zhang C, Shi JP, Liu QW, Chen T, Zhang YY, Jiang W, Zhang LQ, Huang Z, Cong Y

PDB-3jcd:
Structure of Escherichia coli EF4 in posttranslocational ribosomes (Post EF4)
Method: single particle / : Zhang D, Yan K, Liu G, Song G, Luo J, Shi Y, Cheng E, Wu S, Jiang T, Low J, Gao N, Qin Y

PDB-3jce:
Structure of Escherichia coli EF4 in pretranslocational ribosomes (Pre EF4)
Method: single particle / : Zhang D, Yan K, Liu G, Song G, Luo J, Shi Y, Cheng E, Wu S, Jiang T, Low J, Gao N, Qin Y

PDB-3jaa:
HUMAN DNA POLYMERASE ETA in COMPLEX WITH NORMAL DNA AND INCO NUCLEOTIDE (NRM)
Method: single particle / : Lau WCY, Li Y, Zhang Q, Huen MSY

PDB-3ja9:
Structure of native human PCNA
Method: single particle / : Lau WCY, Li Y, Zhang Q, Huen MSY

PDB-3jbl:
Cryo-EM Structure of the Activated NAIP2/NLRC4 Inflammasome Reveals Nucleated Polymerization
Method: single particle / : Zhang L, Chen S, Ruan J, Wu J, Tong AB, Yin Q, Li Y, David L, Lu A, Wang WL, Marks C, Ouyang Q, Zhang X, Mao Y, Wu H

PDB-5ady:
Cryo-EM structures of the 50S ribosome subunit bound with HflX
Method: single particle / : Zhang Y, Mandava CS, Cao W, Li X, Zhang D, Li N, Zhang Y, Zhang X, Qin Y, Mi K, Lei J, Sanyal S, Gao N

PDB-3ja8:
Cryo-EM structure of the MCM2-7 double hexamer
Method: single particle / : Li N, Zhai Y, Zhang Y, Li W, Yang M, Lei J, Tye BK, Gao N

PDB-3ja7:
Cryo-EM structure of the bacteriophage T4 portal protein assembly at near-atomic resolution
Method: single particle / : Sun L, Zhang X, Gao S, Rao PA, Padilla-Sanchez V, Chen Z, Sun S, Xiang Y, Subramaniam S, Rao VB, Rossmann MG

PDB-3j8h:
Structure of the rabbit ryanodine receptor RyR1 in complex with FKBP12 at 3.8 Angstrom resolution
Method: single particle / : Yan Z, Bai X, Yan C, Wu J, Scheres SHW, Shi Y, Yan N

PDB-3j8g:
Electron cryo-microscopy structure of EngA bound with the 50S ribosomal subunit
Method: single particle / : Zhang X, Yan K, Zhang Y, Li N, Ma C, Li Z, Zhang Y, Feng B, Liu J, Sun Y, Xu Y, Lei J, Gao N

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Oct 4, 2017. Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

  • Jacques Dubochet (University of Lausanne, Switzerland) is a pioneer of ice-embedding method of EM specimen (as known as cryo-EM), Most of 3DEM structures in EMDB and PDB are obtained using his method.
  • Joachim Frank (Columbia University, New York, USA) is a pioneer of single particle reconstruction, which is the most used reconstruction method for 3DEM structures in EMDB and EM entries in PDB. And also, he is a develper of Spider, which is one of the most famous software in this field, and is used for some EM Navigor data (e.g. map projection/slice images).
  • Richard Henderson (MRC Laboratory of Molecular Biology, Cambridge, UK) was determined the first biomolecule structure by EM. The first EM entry in PDB, PDB-1brd is determinedby him.

External links: The 2017 Nobel Prize in Chemistry - Press Release

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