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Showing 1 - 50 of 87 items for author: x. & yu

PDB-5xwy:
Electron cryo-microscopy structure of LbuCas13a-crRNA binary complex
Method: single particle / : Zhang X, Wang Y, Ma J, Liu L, Li X, Li Z, You L, Wang J, Wang M

PDB-5y3r:
Cryo-EM structure of Human DNA-PK Holoenzyme
Method: single particle / : Yin X, Liu M, Tian Y, Wang J, Xu Y

PDB-5uzb:
Cryo-EM structure of the MAL TIR domain filament
Method: helical / : Ve T, Vajjhala PR, Hedger A, Croll T, DiMaio F, Horsefield S, Yu X, Lavrencic P, Hassan Z, Morgan GP, Mansell A, Mobli M, O'Carrol A, Chauvin B, Gambin Y, Sierecki E, Landsberg MJ, Stacey KJ, Egelman EH, Kobe B

PDB-5w7g:
An envelope of a filamentous hyperthermophilic virus carries lipids in a horseshoe conformation
Method: helical / : Kasson P, DiMaio F, Yu X, Lucas-Staat S, Krupovic M, Schouten S, Prangishvili D, Egelman E

PDB-5vku:
An atomic structure of the human cytomegalovirus (HCMV) capsid with its securing layer of pp150 tegument protein
Method: single particle / : Yu X, Jih J, Jiang J, Zhou H

PDB-5tx1:
Cryo-Electron microscopy structure of species-D human adenovirus 26
Method: single particle / : Reddy V, Yu X, Veesler D

PDB-5wsn:
Structure of Japanese encephalitis virus
Method: single particle / : Wang X, Zhu L, Li S, Yuan S, Qin C, Fry EE, Stuart ID, Rao Z

PDB-5x58:
Prefusion structure of SARS-CoV spike glycoprotein, conformation 1
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x59:
Prefusion structure of MERS-CoV spike glycoprotein, three-fold symmetry
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x5b:
Prefusion structure of SARS-CoV spike glycoprotein, conformation 2
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x5c:
Prefusion structure of MERS-CoV spike glycoprotein, conformation 1
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x5f:
Prefusion structure of MERS-CoV spike glycoprotein, conformation 2
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x0x:
Complex of Snf2-Nucleosome complex with Snf2 bound to position +6 of the nucleosome
Method: single particle / : Li M, Liu X, Xia X, Chen Z, Li X

PDB-5x0y:
Complex of Snf2-Nucleosome complex with Snf2 bound to SHL2 of the nucleosome
Method: single particle / : Li M, Liu X, Xia X, Chen Z, Li X

PDB-5muu:
dsRNA bacteriophage phi6 nucleocapsid
Method: single particle / : Sun Z, El Omari K, Sun X, Ilca SL, Kotecha A, Stuart DI, Poranen MM, Huiskonen JT

PDB-5muv:
Atomic structure fitted into a localized reconstruction of bacteriophage phi6 packaging hexamer P4
Method: single particle / : Sun Z, El Omari K, Sun X, Ilca S, Kotecha A, Stuart DI, Poranen MM, Huiskonen JT

PDB-5muw:
Atomic structure of P4 packaging enzyme fitted into a localized reconstruction of bacteriophage phi6 vertex
Method: single particle / : Sun Z, El Omari K, Sun X, Ilca S, Kotecha A, Stuart DI, Poranen MM, Huiskonen JT

PDB-5u0p:
Cryo-EM structure of the transcriptional Mediator
Method: single particle / : Tsai KL, Yu X, Gopalan S, Chao TC, Zhang Y, Florens L, Washburn MP, Murakami K, Conaway RC, Conaway JW, Asturias F

PDB-5u0s:
Cryo-EM structure of the Mediator-RNAPII complex
Method: single particle / : Tsai KL, Yu X, Gopalan S, Chao TC, Zhang Y, Florens L, Washburn MP, Murakami K, Conaway RC, Conaway JW, Asturias F

PDB-5h0r:
RNA dependent RNA polymerase ,vp4,dsRNA
Method: single particle / : Li X, Zhou N, Chen W, Zhu B, Wang X, Xu B, Wang J, Liu H, Cheng L

PDB-5h0s:
EM Structure of VP1A and VP1B
Method: single particle / : Li X, Zhou N, Xu B, Chen W, Zhu B, Wang X, Wang J, Liu H, Cheng L

PDB-5h3o:
Structure of a eukaryotic cyclic nucleotide-gated channel
Method: single particle / : Li M, Zhou X, Wang S, Michailidis I, Gong Y, Su D, Li H, Li X, Yang J

PDB-5t2a:
CryoEM structure of the Leishmania donovani 80S ribosome at 2.9 Angstrom resolution
Method: single particle / : Zhang X, Lai M, Zhou ZH

PDB-5t2c:
CryoEM structure of the human ribosome at 3.6 Angstrom resolution
Method: single particle / : Zhang X, Lai M, Zhou ZH

PDB-5wte:
Cryo-EM structure for Hepatitis A virus full particle
Method: single particle / : Wang X, Zhu L, Dang M, Hu Z, Gao Q, Yuan S, Sun Y, Zhang B, Ren J, Walter TS, Wang J, Fry EE, Stuart DI, Rao Z

PDB-5wtf:
Cryo-EM structure for Hepatitis A virus empty particle
Method: single particle / : Wang X, Zhu L, Dang M, Hu Z, Gao Q, Yuan S, Sun Y, Zhang B, Ren J, Walter TS, Wang J, Fry EE, Stuart DI, Rao Z

PDB-5wth:
Cryo-EM structure for Hepatitis A virus complexed with FAB
Method: single particle / : Wang X, Zhu L, Dang M, Hu Z, Gao Q, Yuan S, Sun Y, Zhang B, Ren J, Walter TS, Wang J, Fry EE, Stuart DI, Rao Z

PDB-5tc1:
In situ structures of the genome and genome-delivery apparatus in ssRNA bacteriophage MS2
Method: single particle / : Dai XH, Li ZH, Lai M, Shu S, Du YS, Zhou ZH, Sun R

PDB-5h37:
Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0
Method: single particle / : Zhang S, Kostyuchenko V, Ng TS, Lim XN, Ooi JSG, Lambert S, Tan TY, Widman D, Shi J, Baric RS, Lok SM

PDB-5kua:
Cryo-EM reconstruction of Neisseria meningitidis Type IV pilus
Method: helical / : Kolappan S, Coureuil M, Yu X, Nassif X, Craig L, Egelman EH

PDB-5gka:
cryo-EM structure of human Aichi virus
Method: single particle / : Zhu L, Wang XX, Ren JS, Tuthill TJ, Fry EE, Rao ZH, Stuart DI

PDB-5gqh:
Cryo-EM structure of PaeCas3-AcrF3 complex
Method: single particle / : Zhang X, Ma J, Wang Y, Wang J

PDB-5j8v:
Structure of rabbit ryanodine receptor RyR1 open state activated by calcium ion
Method: single particle / : Wang X, Wei R, Yin C, Sun F

PDB-3jb8:
Insight into Three-dimensional structure of Maize Chlorotic Mottle Virus Revealed by Single Particle Analysis
Method: single particle / : Wang CY, Zhang QF, Gao YZ, Zhou XP, Ji G, Huang XJ, Hong J, Zhang CX

PDB-5jnx:
The 6.6 A cryo-EM structure of the full-length human NPC1 in complex with the cleaved glycoprotein of Ebola virus
Method: single particle / : Gong X, Qian HW, Zhou XH, Wu JP, Wan T, Shi Y, Gao F, Zhou Q, Yan N

PDB-3jct:
Cryo-em structure of eukaryotic pre-60S ribosomal subunits
Method: single particle / : Wu S, Kumcuoglu B, Yan KG, Brown H, Zhang YX, Tan D, Gamalinda M, Yuan Y, Li ZF, Jakovljevic J, Ma CY, Lei JL, Dong MQ, Woolford Jr JL, Gao N

PDB-3jd8:
cryo-EM structure of the full-length human NPC1 at 4.4 angstrom
Method: single particle / : Gong X, Qian HW, Zhou XH, Wu JP, Zhou Q, Yan N

PDB-5jb1:
Pseudo-atomic structure of Human Papillomavirus Type 59 L1 Virus-like Particle
Method: single particle / : Li ZH, Yan XD, Yu H, Zheng QB, Gu Y, Li SW

PDB-3j9d:
Atomic structure of a non-enveloped virus reveals pH sensors for a coordinated process of cell entry
Method: single particle / : Zhang X, Patel A, Celma C, Roy P, Zhou ZH

PDB-3j9e:
Atomic structure of a non-enveloped virus reveals pH sensors for a coordinated process of cell entry
Method: single particle / : Zhang X, Patel A, Celma C, Roy P, Zhou ZH

PDB-3jbt:
Atomic structure of the Apaf-1 apoptosome
Method: single particle / : Zhou M, Li Y, Hu Q, Bai X, Huang W, Yan C, Scheres SHW, Shi Y

PDB-5fj5:
Structure of the in vitro assembled bacteriophage phi6 polymerase complex
Method: single particle / : Ilca S, Kotecha A, Sun X, Poranen MP, Stuart DI, Huiskonen JT

PDB-5fj6:
Structure of the P2 polymerase inside in vitro assembled bacteriophage phi6 polymerase complex
Method: single particle / : Ilca S, Kotecha A, Sun X, Poranen MP, Stuart DI, Huiskonen JT

PDB-5fj7:
Structure of the P2 polymerase inside in vitro assembled bacteriophage phi6 polymerase complex, with P1 included
Method: single particle / : Ilca S, Kotecha A, Sun X, Poranen MP, Stuart DI, Huiskonen JT

PDB-3jb6:
In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus
Method: single particle / : Zhang X, Ding K, Yu XK, Chang W, Sun JC, Zhou ZH

PDB-3jb7:
In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus
Method: single particle / : Zhang X, Ding K, Yu XK, Chang W, Sun JC, Zhou ZH

PDB-3jay:
Atomic model of transcribing cytoplasmic polyhedrosis virus
Method: single particle / : Yu XK, Jiang JS, Sun JC, Zhou ZH

PDB-3jaz:
Atomic model of cytoplasmic polyhedrosis virus with ATP
Method: single particle / : Yu XK, Jiang JS, Sun JC, Zhou ZH

PDB-3jb0:
Atomic model of cytoplasmic polyhedrosis virus with GTP
Method: single particle / : Yu XK, Jiang JS, Sun JC, Zhou ZH

PDB-3jb1:
Atomic model of cytoplasmic polyhedrosis virus with SAM
Method: single particle / : Yu XK, Jiang JS, Sun JC, Zhou ZH

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Oct 4, 2017. Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

  • Jacques Dubochet (University of Lausanne, Switzerland) is a pioneer of ice-embedding method of EM specimen (as known as cryo-EM), Most of 3DEM structures in EMDB and PDB are obtained using his method.
  • Joachim Frank (Columbia University, New York, USA) is a pioneer of single particle reconstruction, which is the most used reconstruction method for 3DEM structures in EMDB and EM entries in PDB. And also, he is a develper of Spider, which is one of the most famous software in this field, and is used for some EM Navigor data (e.g. map projection/slice images).
  • Richard Henderson (MRC Laboratory of Molecular Biology, Cambridge, UK) was determined the first biomolecule structure by EM. The first EM entry in PDB, PDB-1brd is determinedby him.

External links: The 2017 Nobel Prize in Chemistry - Press Release

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