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Showing 1 - 50 of 147 items for author: j. & zhang

PDB-6b7z:
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11 heavy chain and FAB H11 light chain
Method: single particle / : Liang WG, Zhang Z, Bailey LJ, Kossiakoff AA, Tan YZ, Wei H, Carragher B, Potter SC, Tang WJ

PDB-6b70:
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain and insulin
Method: single particle / : Liang WG, Zhang Z, Bailey LJ, Kossiakoff AA, Tan YZ, Wei H, Carragher B, Potter SC, Tang WJ

PDB-6bfc:
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
Method: single particle / : Liang WG, Zhang Z, Bailey LJ, Kossiakoff AA, Tan YZ, Wei H, Carragher B, Potter SC, Tang WJ

PDB-5oaf:
Human Rvb1/Rvb2 heterohexamer in INO80 complex
Method: single particle / : Aramayo RJ, Bythell-Douglas R, Ayala R, Willhoft O, Wigley D, Zhang X

PDB-6bq1:
Human PI4KIIIa lipid kinase complex
Method: single particle / : Lees JA, Zhang Y, Oh M, Schauder CM, Yu X, Baskin J, Dobbs K, Notarangelo LD, Camilli PD, Walz T, Reinisch KM

PDB-5up4:
Structure of the HIV-1 Capsid Protein and spacer peptide 1 by Cryo-EM
Method: helical / : Perilla JR, Schirra R, Zhang P, Schulten K

PDB-6b3q:
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
Method: single particle / : Liang WG, Zhang Z, Bailey LJ, Kossiakoff AA, Tan YZ, Wei H, Carragher B, Potter SC, Tang WJ

PDB-5uz5:
S. cerevisiae U1 snRNP
Method: single particle / : Li X, Liu S, Jiang J, Zhang L, Espinosa S, Hill RC, Hansen KC, Zhou ZH, Zhao R

PDB-5y6p:
Structure of the phycobilisome from the red alga Griffithsia pacifica
Method: single particle / : Zhang J, Ma JF, Liu DS, Sun S, Sui SF

PDB-6b7y:
Cryo-EM structure of human insulin degrading enzyme
Method: single particle / : Liang WG, Zhang Z, Bailey LJ, Kossiakoff AA, Tan YZ, Wei H, Carragher B, Potter SC, Tang WJ

PDB-5yhq:
Cryo-EM Structure of CVA6 VLP
Method: single particle / : Chen J, Zhang C, Huang Z, Cong Y

PDB-6b7n:
Cryo-electron microscopy structure of porcine delta coronavirus spike protein in the pre-fusion state
Method: single particle / : Shang J, Zheng Y, Yang Y, Liu C, Geng Q, Tai W, Du L, Zhou Y, Zhang W, Li F

PDB-5vly:
Asymmetric unit for the coat proteins of phage Qbeta
Method: single particle / : Cui Z, Zhang J

PDB-5vlz:
Backbone model for phage Qbeta capsid
Method: single particle / : Cui Z, Zhang J

PDB-5vm7:
Pseudo-atomic model of the MurA-A2 complex
Method: single particle / : Cui Z, Zhang J

PDB-5m50:
Mechanism of microtubule minus-end recognition and protection by CAMSAP proteins
Method: single particle / : Akhmanova A, Moores CA, Baldus M, Steinmetz MO, Topf M, Roberts AJ, Grant BJ, Scarabelli G, Joseph AP, van Hooff JJE, Houben K, Hua S, Luo Y, Stangier MM, Jiang K, Atherton J

PDB-5m54:
Mechanism of microtubule minus-end recognition and protection by CAMSAP proteins
Method: single particle / : Akhmanova A, Moores CA, Baldus M, Steinmetz MO, Topf M, Roberts AJ, Grant BJ, Scarabelli G, Joseph AJ, van Hooff JJE, Houben K, Hua S, Luo Y, Stangier MM, Jiang K, Atherton J

PDB-5m5c:
Mechanism of microtubule minus-end recognition and protection by CAMSAP proteins
Method: single particle / : Akhmanova A, Moores CA, Baldus M, Steinmetz MO, Topf M, Roberts AJ, Grant BJ, Scarabelli G, Joseph AP, van Hooff JJE, Houben K, Hua S, Luo Y, Stangier MM, Jiang K, Atherton J

PDB-5v7q:
Cryo-EM structure of the large ribosomal subunit from Mycobacterium tuberculosis bound with a potent linezolid analog
Method: single particle / : Yang K, Chang JY, Cui Z, Zhang J

PDB-5v93:
Cryo-EM structure of the 70S ribosome from Mycobacterium tuberculosis bound with Capreomycin
Method: single particle / : Yang K, Chang JY, Cui Z, Li X, Meng R, Duan L, Thongchol J, Jakana J, Huwe C, Sacchettini J, Zhang J

PDB-5xnl:
Structure of stacked C2S2M2-type PSII-LHCII supercomplex from Pisum sativum
Method: single particle / : Su XD, Ma J, Wei XP, Cao P, Zhu DJ, Chang WR, Liu ZF, Zhang XZ, Li M

PDB-5xnm:
Structure of unstacked C2S2M2-type PSII-LHCII supercomplex from Pisum sativum
Method: single particle / : Su XD, Ma J, Wei XP, Cao P, Zhu DJ, Chang WR, Liu ZF, Zhang XZ, Li M

PDB-5xnn:
Structure of M-LHCII and CP24 complexes in the stacked C2S2M2-type PSII-LHCII supercomplex from Pisum sativum
Method: single particle / : Su XD, Ma J, Wei XP, Cao P, Zhu DJ, Chang WR, Liu ZF, Zhang XZ, Li M

PDB-5xno:
Structure of M-LHCII and CP24 complexes in the unstacked C2S2M2-type PSII-LHCII supercomplex from Pisum sativum
Method: single particle / : Su XD, Ma J, Wei XP, Cao P, Zhu DJ, Chang WR, Liu ZF, Zhang XZ, Li M

PDB-5xwy:
Electron cryo-microscopy structure of LbuCas13a-crRNA binary complex
Method: single particle / : Zhang X, Wang Y, Ma J, Liu L, Li X, Li Z, You L, Wang J, Wang M

PDB-5w81:
Phosphorylated, ATP-bound structure of zebrafish cystic fibrosis transmembrane conductance regulator (CFTR)
Method: single particle / : Zhang Z, Liu F, Chen J

PDB-5xjc:
Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom
Method: single particle / : Zhang X, Yan C, Hang J, Finci IL, Lei J, Shi Y

PDB-5uf6:
The 2.8 A Electron Microscopy Structure of Adeno-Associated Virus-DJ Bound by a Heparanoid Pentasaccharide
Method: single particle / : Xie Q, Spear JM, Noble AJ, Sousa DR, Meyer NL, Davulcu O, Zhang F, Linhardt RJ, Stagg SM, Chapman M

PDB-5vai:
Cryo-EM structure of the activated Glucagon-like peptide-1 receptor in complex with G protein
Method: single particle / : Zhang Y, Sun B, Feng D, Hu H, Chu M, Qu Q, Tarrasch JT, Li S, Kobilka TS, Kobilka BK, Skiniotis G

PDB-5uz7:
Volta phase plate cryo-electron microscopy structure of a calcitonin receptor-heterotrimeric Gs protein complex
Method: single particle / : Liang YL, Khoshouei M, Radjainia M, Zhang Y, Glukhova A, Tarrasch J, Thal DM, Furness SGB, Christopoulos G, Coudrat T, Danev R, Baumeister W, Miller LJ, Christopoulos A, Kobilka BK, Wootten D, Skiniotis G, Sexton PM

PDB-5x58:
Prefusion structure of SARS-CoV spike glycoprotein, conformation 1
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x59:
Prefusion structure of MERS-CoV spike glycoprotein, three-fold symmetry
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x5b:
Prefusion structure of SARS-CoV spike glycoprotein, conformation 2
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x5c:
Prefusion structure of MERS-CoV spike glycoprotein, conformation 1
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x5f:
Prefusion structure of MERS-CoV spike glycoprotein, conformation 2
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5mz6:
Cryo-EM structure of a Separase-Securin complex from Caenorhabditis elegans at 3.8 A resolution
Method: single particle / : Boland A, Martin TG, Zhang Z, Yang J, Bai XC, Chang L, Scheres SHW, Barford D

PDB-5u0p:
Cryo-EM structure of the transcriptional Mediator
Method: single particle / : Tsai KL, Yu X, Gopalan S, Chao TC, Zhang Y, Florens L, Washburn MP, Murakami K, Conaway RC, Conaway JW, Asturias F

PDB-5u0s:
Cryo-EM structure of the Mediator-RNAPII complex
Method: single particle / : Tsai KL, Yu X, Gopalan S, Chao TC, Zhang Y, Florens L, Washburn MP, Murakami K, Conaway RC, Conaway JW, Asturias F

PDB-5x0m:
Structure of a eukaryotic voltage-gated sodium channel at near atomic resolution
Method: single particle / : Shen H, Zhou Q, Pan X, Li Z, Wu J, Yan N

PDB-5upw:
CryoEM Structure Refinement by Integrating NMR Chemical Shifts with Molecular Dynamics Simulations
Method: helical / : Perilla JR

PDB-5u8t:
Structure of Eukaryotic CMG Helicase at a Replication Fork and Implications
Method: single particle / : Li B, Georgescu R, Yuan Z, Santos R, Sun J, Zhang D, Yurieva O, Li H, O'Donnell ME

PDB-5u8s:
Structure of eukaryotic CMG helicase at a replication fork
Method: single particle / : Li H, Li B, Georgescu R, Yuan Z, Santos R, Sun J, Zhang D, Yurieva O, O'Donnell ME

PDB-5wte:
Cryo-EM structure for Hepatitis A virus full particle
Method: single particle / : Wang X, Zhu L, Dang M, Hu Z, Gao Q, Yuan S, Sun Y, Zhang B, Ren J, Walter TS, Wang J, Fry EE, Stuart DI, Rao Z

PDB-5wtf:
Cryo-EM structure for Hepatitis A virus empty particle
Method: single particle / : Wang X, Zhu L, Dang M, Hu Z, Gao Q, Yuan S, Sun Y, Zhang B, Ren J, Walter TS, Wang J, Fry EE, Stuart DI, Rao Z

PDB-5wth:
Cryo-EM structure for Hepatitis A virus complexed with FAB
Method: single particle / : Wang X, Zhu L, Dang M, Hu Z, Gao Q, Yuan S, Sun Y, Zhang B, Ren J, Walter TS, Wang J, Fry EE, Stuart DI, Rao Z

PDB-5uak:
Dephosphorylated, ATP-free human cystic fibrosis transmembrane conductance regulator (CFTR)
Method: single particle / : Liu F, Zhang Z, Chen J

PDB-5uar:
Dephosphorylated, ATP-free cystic fibrosis transmembrane conductance regulator (CFTR) from zebrafish
Method: single particle / : Zhang Z, Chen J

PDB-5h37:
Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0
Method: single particle / : Zhang S, Kostyuchenko V, Ng TS, Lim XN, Ooi JSG, Lambert S, Tan TY, Widman D, Shi J, Baric RS, Lok SM

PDB-5l9t:
Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with E2 UBE2S poised for polyubiquitination where UBE2S, APC2, and APC11 are modeled into low resolution density
Method: single particle / : Brown NG, VanderLinden R, Dube P, Haselbach D, Peters JM, Stark H, Schulman BA

PDB-3jbm:
Electron cryo-microscopy of a virus-like particle of orange-spotted grouper nervous necrosis virus
Method: single particle / : Xie J, Li K, Gao Y, Huang R, Lai Y, Shi Y, Yang S, Zhu G, Zhang Q, He J

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Oct 4, 2017. Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

  • Jacques Dubochet (University of Lausanne, Switzerland) is a pioneer of ice-embedding method of EM specimen (as known as cryo-EM), Most of 3DEM structures in EMDB and PDB are obtained using his method.
  • Joachim Frank (Columbia University, New York, USA) is a pioneer of single particle reconstruction, which is the most used reconstruction method for 3DEM structures in EMDB and EM entries in PDB. And also, he is a develper of Spider, which is one of the most famous software in this field, and is used for some EM Navigor data (e.g. map projection/slice images).
  • Richard Henderson (MRC Laboratory of Molecular Biology, Cambridge, UK) was determined the first biomolecule structure by EM. The first EM entry in PDB, PDB-1brd is determinedby him.

External links: The 2017 Nobel Prize in Chemistry - Press Release

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