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Showing 1 - 50 of 93 items for author: j. & wang

PDB-5up4:
Structure of the HIV-1 Capsid Protein and spacer peptide 1 by Cryo-EM
Method: helical / : Perilla JR, Schirra R, Zhang P, Schulten K

PDB-5wk5:
Cryo-EM structure of P. aeruginosa flagellar filaments A443V
Method: helical / : Wang F, Postel S, Sundberg EJ, Egelman EH

PDB-5wk6:
Cryo-EM structure of P. aeruginosa flagellar filaments G420A
Method: helical / : Wang F, Postel S, Sundberg EJ, Egelman EH

PDB-5y0a:
Cryo-EM structure of zika virus complexed with Fab of ZKA190 at pH 8.0 and 37 celsius degree
Method: single particle / : Wang JQ, Lok SM

PDB-5xwy:
Electron cryo-microscopy structure of LbuCas13a-crRNA binary complex
Method: single particle / : Zhang X, Wang Y, Ma J, Liu L, Li X, Li Z, You L, Wang J, Wang M

PDB-5y3r:
Cryo-EM structure of Human DNA-PK Holoenzyme
Method: single particle / : Yin X, Liu M, Tian Y, Wang J, Xu Y

PDB-5w9h:
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Method: single particle / : Pallesen J, Ward AB

PDB-5w9i:
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Method: single particle / : Pallesen J, Ward AB

PDB-5w9j:
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Method: single particle / : Pallesen J, Ward AB

PDB-5w9k:
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Method: single particle / : Pallesen J, Ward AB

PDB-5w9l:
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Method: single particle / : Pallesen J, Ward AB

PDB-5w9m:
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Method: single particle / : Pallesen J, Ward AB

PDB-5w9n:
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Method: single particle / : Pallesen J, Ward AB

PDB-5w9o:
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Method: single particle / : Pallesen J, Ward AB

PDB-5w9p:
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Method: single particle / : Pallesen J, Ward AB

PDB-5ojq:
The modeled structure of of wild type extended type VI secretion system sheath/tube complex in vibrio cholerae based on cryo-EM reconstruction of the non-contractile sheath/tube complex
Method: helical / : Wang J, Brackmann M, Castano-Diez D, Kudryashev M, Goldie K, Maier T, Stahlberg H, Basler M

PDB-5xsy:
Structure of the Nav1.4-beta1 complex from electric eel
Method: single particle / : Yan Z, Zhou Q, Wu JP, Yan N

PDB-5mxn:
Atomic model of the VipA/VipB/Hcp, the type six secretion system non-contractile sheath-tube of Vibrio cholerae from cryo-EM
Method: helical / : Wang J, Brackmann M, Castano-Diez D, Kudryashev M, Goldie K, Maier T, Stahlberg H, Basler M

PDB-5myu:
VipA-N2/VipB contracted sheath of type VI secretion system
Method: helical / : Wang J, Brackmann B, Castano-Diez D, Kudryashev M, Goldie D, Maier T, Stahlberg H, Basler M

PDB-5viy:
BG505 SOSIP.664 in complex with broadly neutralizing antibodies BG1 and 8ANC195
Method: single particle / : Wang H, Bjorkman PJ

PDB-5vj6:
BG505 SOSIP.664 in complex with broadly neutralizing antibodies PG9 and 8ANC195
Method: single particle / : Wang H, Bjorkman PJ

PDB-5x58:
Prefusion structure of SARS-CoV spike glycoprotein, conformation 1
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x59:
Prefusion structure of MERS-CoV spike glycoprotein, three-fold symmetry
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x5b:
Prefusion structure of SARS-CoV spike glycoprotein, conformation 2
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x5c:
Prefusion structure of MERS-CoV spike glycoprotein, conformation 1
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5x5f:
Prefusion structure of MERS-CoV spike glycoprotein, conformation 2
Method: single particle / : Yuan Y, Cao D, Zhang Y, Ma J, Qi J, Wang Q, Lu G, Wu Y, Yan J, Shi Y, Zhang X, Gao GF

PDB-5ng5:
multi-drug efflux; membrane transport; RND superfamily; Drug resistance
Method: single particle / : Wang Z, Fan G, Hryc CF, Blaza JN, Serysheva II, Schmid MF, Chiu W, Luisi BF, Du D

PDB-5v5s:
multi-drug efflux; membrane transport; RND superfamily; Drug resistance
Method: single particle / : wang Z, fan G, Hryc CF, Blaza JN, Serysheva II, Schmid MF, Chiu W, Luisi BF, Du D

PDB-5uu5:
Bacteriophage P22 mature virion capsid protein
Method: single particle / : Hryc CF, Chen DH, Afonine PV, Jakana J, Wang Z, Haase-Pettingell C, Jiang W, Adams PD, King JA, Schmid MF, Chiu W

PDB-5h0r:
RNA dependent RNA polymerase ,vp4,dsRNA
Method: single particle / : Li X, Zhou N, Chen W, Zhu B, Wang X, Xu B, Wang J, Liu H, Cheng L

PDB-5h0s:
EM Structure of VP1A and VP1B
Method: single particle / : Li X, Zhou N, Xu B, Chen W, Zhu B, Wang X, Wang J, Liu H, Cheng L

PDB-5h3o:
Structure of a eukaryotic cyclic nucleotide-gated channel
Method: single particle / : Li M, Zhou X, Wang S, Michailidis I, Gong Y, Su D, Li H, Li X, Yang J

PDB-5h64:
Cryo-EM structure of mTORC1
Method: single particle / : Yang H, Wang J, Liu M, Chen X, Huang M, Tan D, Dong M, Wong CCL, Wang J, Xu Y, Wang H

PDB-5wte:
Cryo-EM structure for Hepatitis A virus full particle
Method: single particle / : Wang X, Zhu L, Dang M, Hu Z, Gao Q, Yuan S, Sun Y, Zhang B, Ren J, Walter TS, Wang J, Fry EE, Stuart DI, Rao Z

PDB-5wtf:
Cryo-EM structure for Hepatitis A virus empty particle
Method: single particle / : Wang X, Zhu L, Dang M, Hu Z, Gao Q, Yuan S, Sun Y, Zhang B, Ren J, Walter TS, Wang J, Fry EE, Stuart DI, Rao Z

PDB-5wth:
Cryo-EM structure for Hepatitis A virus complexed with FAB
Method: single particle / : Wang X, Zhu L, Dang M, Hu Z, Gao Q, Yuan S, Sun Y, Zhang B, Ren J, Walter TS, Wang J, Fry EE, Stuart DI, Rao Z

PDB-5h1b:
Human RAD51 presynaptic complex
Method: helical / : Xu J, Zhao L, Xu Y, Zhao W, Sung P, Wang HW

PDB-5h1c:
Human RAD51 post-synaptic complexes
Method: helical / : Xu J, Zhao L, Xu Y, Zhao W, Sung P, Wang HW

PDB-5grs:
Complex structure of the fission yeast SREBP-SCAP binding domains
Method: single particle / : Gong X, Qian HW, Wu JP, Yan N

PDB-5thr:
Cryo-EM structure of a BG505 Env-sCD4-17b-8ANC195 complex
Method: single particle / : Wang H, Bjorkman PJ

PDB-5go9:
Cryo-EM structure of RyR2 in closed state
Method: single particle / : Peng W, Wu JP, Yan N

PDB-5goa:
Cryo-EM structure of RyR2 in open state
Method: single particle / : Peng W, Wu JP, Yan N

PDB-5gka:
cryo-EM structure of human Aichi virus
Method: single particle / : Zhu L, Wang XX, Ren JS, Tuthill TJ, Fry EE, Rao ZH, Stuart DI

PDB-5gqh:
Cryo-EM structure of PaeCas3-AcrF3 complex
Method: single particle / : Zhang X, Ma J, Wang Y, Wang J

PDB-3jb8:
Insight into Three-dimensional structure of Maize Chlorotic Mottle Virus Revealed by Single Particle Analysis
Method: single particle / : Wang CY, Zhang QF, Gao YZ, Zhou XP, Ji G, Huang XJ, Hong J, Zhang CX

PDB-3jco:
Structure of yeast 26S proteasome in M1 state derived from Titan dataset
Method: single particle / : Luan B, Huang XL, Wu JP, Shi YG, Wang F

PDB-3jcp:
Structure of yeast 26S proteasome in M2 state derived from Titan dataset
Method: single particle / : Luan B, Huang XL, Wu JP, Shi YG, Wang F

PDB-5g06:
Cryo-EM structure of yeast cytoplasmic exosome
Method: single particle / : Liu JJ, Niu CY, Wu Y, Tan D, Wang Y, Ye MD, Liu Y, Zhao WW, Zhou K, Liu QS, Dai JB, Yang XR, Dong MQ, Huang N, Wang HW

PDB-5jnx:
The 6.6 A cryo-EM structure of the full-length human NPC1 in complex with the cleaved glycoprotein of Ebola virus
Method: single particle / : Gong X, Qian HW, Zhou XH, Wu JP, Wan T, Shi Y, Gao F, Zhou Q, Yan N

PDB-3jd8:
cryo-EM structure of the full-length human NPC1 at 4.4 angstrom
Method: single particle / : Gong X, Qian HW, Zhou XH, Wu JP, Zhou Q, Yan N

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Oct 4, 2017. Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

Three pioneers of this field were awarded Nobel Prize in Chemistry 2017

  • Jacques Dubochet (University of Lausanne, Switzerland) is a pioneer of ice-embedding method of EM specimen (as known as cryo-EM), Most of 3DEM structures in EMDB and PDB are obtained using his method.
  • Joachim Frank (Columbia University, New York, USA) is a pioneer of single particle reconstruction, which is the most used reconstruction method for 3DEM structures in EMDB and EM entries in PDB. And also, he is a develper of Spider, which is one of the most famous software in this field, and is used for some EM Navigor data (e.g. map projection/slice images).
  • Richard Henderson (MRC Laboratory of Molecular Biology, Cambridge, UK) was determined the first biomolecule structure by EM. The first EM entry in PDB, PDB-1brd is determinedby him.

External links: The 2017 Nobel Prize in Chemistry - Press Release

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